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Basic Research
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TRAF3 Modulation: Novel Mechanism for the Anti-inflammatory Effects of the Vitamin D Receptor Agonist Paricalcitol in Renal Disease

Sandra Rayego-Mateos, Jose Luis Morgado-Pascual, José Manuel Valdivielso, Ana Belén Sanz, Enrique Bosch-Panadero, Raúl R. Rodrigues-Díez, Jesús Egido, Alberto Ortiz, Emilio González-Parra and Marta Ruiz-Ortega
JASN September 2020, 31 (9) 2026-2042; DOI: https://doi.org/10.1681/ASN.2019111206
Sandra Rayego-Mateos
1Molecular and Cellular Biology in Renal and Vascular Pathology, Fundación Instituto de Investigación Sanitaria-Fundación Jiménez Díaz,Universidad autonoma de madrid, Madrid, Spain
2Vascular and Renal Translational Research Group. Institut de Receca Biomedica de Lleida (IRBLleida), Lleida, Spain
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Jose Luis Morgado-Pascual
1Molecular and Cellular Biology in Renal and Vascular Pathology, Fundación Instituto de Investigación Sanitaria-Fundación Jiménez Díaz,Universidad autonoma de madrid, Madrid, Spain
3REDinREN (Red de Investigación Renal), Madrid, Spain
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José Manuel Valdivielso
2Vascular and Renal Translational Research Group. Institut de Receca Biomedica de Lleida (IRBLleida), Lleida, Spain
3REDinREN (Red de Investigación Renal), Madrid, Spain
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Ana Belén Sanz
3REDinREN (Red de Investigación Renal), Madrid, Spain
4Laboratory of Nephrology and Hypertension, Fundación Instituto de Investigación Sanitaria-Fundación Jiménez Díaz-Universidad Autónoma Madrid, 28040 Madrid, Spain.
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Enrique Bosch-Panadero
4Laboratory of Nephrology and Hypertension, Fundación Instituto de Investigación Sanitaria-Fundación Jiménez Díaz-Universidad Autónoma Madrid, 28040 Madrid, Spain.
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Raúl R. Rodrigues-Díez
1Molecular and Cellular Biology in Renal and Vascular Pathology, Fundación Instituto de Investigación Sanitaria-Fundación Jiménez Díaz,Universidad autonoma de madrid, Madrid, Spain
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  • ORCID record for Raúl R. Rodrigues-Díez
Jesús Egido
5Renal, Vascular and Diabetes Research Laboratory, IIS-Fundación Jiménez Díaz.Universidad Autónoma. 28040 Madrid, Spain; Spanish Biomedical Research Centre in Diabetes and Associated Metabolic Disorders (CIBERDEM). 28029 Madrid, Spain
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Alberto Ortiz
3REDinREN (Red de Investigación Renal), Madrid, Spain
4Laboratory of Nephrology and Hypertension, Fundación Instituto de Investigación Sanitaria-Fundación Jiménez Díaz-Universidad Autónoma Madrid, 28040 Madrid, Spain.
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Emilio González-Parra
4Laboratory of Nephrology and Hypertension, Fundación Instituto de Investigación Sanitaria-Fundación Jiménez Díaz-Universidad Autónoma Madrid, 28040 Madrid, Spain.
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Marta Ruiz-Ortega
1Molecular and Cellular Biology in Renal and Vascular Pathology, Fundación Instituto de Investigación Sanitaria-Fundación Jiménez Díaz,Universidad autonoma de madrid, Madrid, Spain
3REDinREN (Red de Investigación Renal), Madrid, Spain
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Journal of the American Society of Nephrology: 31 (9)
Journal of the American Society of Nephrology
Vol. 31, Issue 9
September 2020
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TRAF3 Modulation: Novel Mechanism for the Anti-inflammatory Effects of the Vitamin D Receptor Agonist Paricalcitol in Renal Disease
Sandra Rayego-Mateos, Jose Luis Morgado-Pascual, José Manuel Valdivielso, Ana Belén Sanz, Enrique Bosch-Panadero, Raúl R. Rodrigues-Díez, Jesús Egido, Alberto Ortiz, Emilio González-Parra, Marta Ruiz-Ortega
JASN Sep 2020, 31 (9) 2026-2042; DOI: 10.1681/ASN.2019111206

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TRAF3 Modulation: Novel Mechanism for the Anti-inflammatory Effects of the Vitamin D Receptor Agonist Paricalcitol in Renal Disease
Sandra Rayego-Mateos, Jose Luis Morgado-Pascual, José Manuel Valdivielso, Ana Belén Sanz, Enrique Bosch-Panadero, Raúl R. Rodrigues-Díez, Jesús Egido, Alberto Ortiz, Emilio González-Parra, Marta Ruiz-Ortega
JASN Sep 2020, 31 (9) 2026-2042; DOI: 10.1681/ASN.2019111206
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Keywords

  • vitamin D receptor
  • paricalcitol
  • chronic kidney disease
  • inflammation
  • NF-κB
  • TRAF3

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