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Research Letters
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Impaired Humoral but Substantial Cellular Immune Response to Variants of Concern B1.1.7 and B.1.351 in Hemodialysis Patients after Vaccination with BNT162b2

Constantin J. Thieme, Arturo Blazquez-Navarro, Lema Safi, Sviatlana Kaliszczyk, Krystallenia Paniskaki, Isabel E. Neumann, Kita Schmidt, Mara Stockhausen, Jan Hörstrup, Ocan Cinkilic, Linus Flitsch-Kiefner, Toni L. Meister, Corinna Marheinecke, Stephanie Pfaender, Eike Steinmann, Felix S. Seibert, Ulrik Stervbo, Timm H. Westhoff, Toralf Roch and Nina Babel
JASN November 2021, 32 (11) 2725-2727; DOI: https://doi.org/10.1681/ASN.2021050672
Constantin J. Thieme
1Berlin Center for Advanced Therapies, Charité—Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, Berlin, Germany
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  • ORCID record for Constantin J. Thieme
Arturo Blazquez-Navarro
1Berlin Center for Advanced Therapies, Charité—Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, Berlin, Germany
2Center for Translational Medicine and Immune Diagnostics Laboratory, Medical Department I, Marien Hospital Herne, University Hospital of the Ruhr–University Bochum, Herne, Germany
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Lema Safi
2Center for Translational Medicine and Immune Diagnostics Laboratory, Medical Department I, Marien Hospital Herne, University Hospital of the Ruhr–University Bochum, Herne, Germany
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Sviatlana Kaliszczyk
2Center for Translational Medicine and Immune Diagnostics Laboratory, Medical Department I, Marien Hospital Herne, University Hospital of the Ruhr–University Bochum, Herne, Germany
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Krystallenia Paniskaki
3Department of Infectious Diseases, West German Centre of Infectious Diseases, University Hospital Essen, University Duisburg-Essen, Essen, Germany
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Isabel E. Neumann
1Berlin Center for Advanced Therapies, Charité—Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, Berlin, Germany
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Kita Schmidt
1Berlin Center for Advanced Therapies, Charité—Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, Berlin, Germany
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Mara Stockhausen
2Center for Translational Medicine and Immune Diagnostics Laboratory, Medical Department I, Marien Hospital Herne, University Hospital of the Ruhr–University Bochum, Herne, Germany
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Jan Hörstrup
4Kuratorium für Dialyse und Nierentransplantat, Berlin, Germany
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Ocan Cinkilic
5Dialyse Schwerte, Schwerte, Germany
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Linus Flitsch-Kiefner
6Kuratorium für Dialyse und Nierentransplantat, Hagen, Germany
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Toni L. Meister
7Department of Molecular and Medical Virology, Ruhr University, Bochum, Germany
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Corinna Marheinecke
7Department of Molecular and Medical Virology, Ruhr University, Bochum, Germany
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Stephanie Pfaender
7Department of Molecular and Medical Virology, Ruhr University, Bochum, Germany
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Eike Steinmann
7Department of Molecular and Medical Virology, Ruhr University, Bochum, Germany
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Felix S. Seibert
2Center for Translational Medicine and Immune Diagnostics Laboratory, Medical Department I, Marien Hospital Herne, University Hospital of the Ruhr–University Bochum, Herne, Germany
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Ulrik Stervbo
2Center for Translational Medicine and Immune Diagnostics Laboratory, Medical Department I, Marien Hospital Herne, University Hospital of the Ruhr–University Bochum, Herne, Germany
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Timm H. Westhoff
2Center for Translational Medicine and Immune Diagnostics Laboratory, Medical Department I, Marien Hospital Herne, University Hospital of the Ruhr–University Bochum, Herne, Germany
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Toralf Roch
1Berlin Center for Advanced Therapies, Charité—Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, Berlin, Germany
2Center for Translational Medicine and Immune Diagnostics Laboratory, Medical Department I, Marien Hospital Herne, University Hospital of the Ruhr–University Bochum, Herne, Germany
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Nina Babel
1Berlin Center for Advanced Therapies, Charité—Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, Berlin, Germany
2Center for Translational Medicine and Immune Diagnostics Laboratory, Medical Department I, Marien Hospital Herne, University Hospital of the Ruhr–University Bochum, Herne, Germany
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Journal of the American Society of Nephrology: 32 (11)
Journal of the American Society of Nephrology
Vol. 32, Issue 11
November 2021
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Impaired Humoral but Substantial Cellular Immune Response to Variants of Concern B1.1.7 and B.1.351 in Hemodialysis Patients after Vaccination with BNT162b2
Constantin J. Thieme, Arturo Blazquez-Navarro, Lema Safi, Sviatlana Kaliszczyk, Krystallenia Paniskaki, Isabel E. Neumann, Kita Schmidt, Mara Stockhausen, Jan Hörstrup, Ocan Cinkilic, Linus Flitsch-Kiefner, Toni L. Meister, Corinna Marheinecke, Stephanie Pfaender, Eike Steinmann, Felix S. Seibert, Ulrik Stervbo, Timm H. Westhoff, Toralf Roch, Nina Babel
JASN Nov 2021, 32 (11) 2725-2727; DOI: 10.1681/ASN.2021050672

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Impaired Humoral but Substantial Cellular Immune Response to Variants of Concern B1.1.7 and B.1.351 in Hemodialysis Patients after Vaccination with BNT162b2
Constantin J. Thieme, Arturo Blazquez-Navarro, Lema Safi, Sviatlana Kaliszczyk, Krystallenia Paniskaki, Isabel E. Neumann, Kita Schmidt, Mara Stockhausen, Jan Hörstrup, Ocan Cinkilic, Linus Flitsch-Kiefner, Toni L. Meister, Corinna Marheinecke, Stephanie Pfaender, Eike Steinmann, Felix S. Seibert, Ulrik Stervbo, Timm H. Westhoff, Toralf Roch, Nina Babel
JASN Nov 2021, 32 (11) 2725-2727; DOI: 10.1681/ASN.2021050672
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  • Patient Activation Measure in Dialysis-Dependent Patients in the United States
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Keywords

  • chronic hemodialysis
  • clinical immunology
  • kidney disease
  • SARS-CoV-2
  • Vaccination
  • infectious diseases
  • mRNA vaccine
  • immunity
  • cellular
  • COVID-19

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