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Table of Contents

January 2021; Volume 32,Issue 1

This Month's Highlights

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    This Month's Highlights
    JASN January 2021, 32 (1) i; DOI: https://doi.org/10.1681/ASN.2020111605
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Up Front Matters

  • Editorials

    • Open Access
      COVID-19 and APOL1: Understanding Disease Mechanisms through Clinical Observation
      David J. Friedman
      JASN January 2021, 32 (1) 1-2; DOI: https://doi.org/10.1681/ASN.2020111629
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      The Aftermath of AKI: Recurrent AKI, Acute Kidney Disease, and CKD Progression
      Yumeng Wen and Chirag R. Parikh
      JASN January 2021, 32 (1) 2-4; DOI: https://doi.org/10.1681/ASN.2020091317
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    • Open Access
      COVID-19–Associated Acute Kidney Injury: Learning from the First Wave
      Ron Wald and Sean M. Bagshaw
      JASN January 2021, 32 (1) 4-6; DOI: https://doi.org/10.1681/ASN.2020101401
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      Will Targeting Interleukin-6 in the Anemia of CKD Change Our Treatment Paradigm?
      Daniel W. Coyne and Robert Fleming
      JASN January 2021, 32 (1) 6-8; DOI: https://doi.org/10.1681/ASN.2020101476
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  • Review

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      Sphingosine-1-Phosphate Metabolism and Signaling in Kidney Diseases
      Yelena Drexler, Judith Molina, Alla Mitrofanova, Alessia Fornoni and Sandra Merscher
      JASN January 2021, 32 (1) 9-31; DOI: https://doi.org/10.1681/ASN.2020050697
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Rapid Communication

  • COVID-19–Associated Glomerular Disease
    Open Access
    COVID-19–Associated Glomerular Disease
    Aneesha A. Shetty, Ibrahim Tawhari, Luisa Safar-Boueri, Nay Seif, Ameen Alahmadi, Richard Gargiulo, Vikram Aggarwal, Irtaza Usman, Sergey Kisselev, Ali G. Gharavi, Yahspal Kanwar and Susan E. Quaggin
    JASN January 2021, 32 (1) 33-40; DOI: https://doi.org/10.1681/ASN.2020060804
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Basic Research

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    Cyclin-Dependent Kinase 1 Activity Is a Driver of Cyst Growth in Polycystic Kidney Disease
    Chao Zhang, Bruno Balbo, Ming Ma, Jun Zhao, Xin Tian, Yuval Kluger and Stefan Somlo
    JASN January 2021, 32 (1) 41-51; DOI: https://doi.org/10.1681/ASN.2020040511
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  • Deep Learning–Based Segmentation and Quantification in Experimental Kidney Histopathology
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    Deep Learning–Based Segmentation and Quantification in Experimental Kidney Histopathology
    Nassim Bouteldja, Barbara M. Klinkhammer, Roman D. Bülow, Patrick Droste, Simon W. Otten, Saskia Freifrau von Stillfried, Julia Moellmann, Susan M. Sheehan, Ron Korstanje, Sylvia Menzel, Peter Bankhead, Matthias Mietsch, Charis Drummer, Michael Lehrke, Rafael Kramann, Jürgen Floege, Peter Boor and Dorit Merhof
    JASN January 2021, 32 (1) 52-68; DOI: https://doi.org/10.1681/ASN.2020050597
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  • Neutrophil-Macrophage Imbalance Drives the Development of Renal Scarring during Experimental Pyelonephritis
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    Neutrophil-Macrophage Imbalance Drives the Development of Renal Scarring during Experimental Pyelonephritis
    Juan de Dios Ruiz-Rosado, Frank Robledo-Avila, Hanna Cortado, Javier Rangel-Moreno, Sheryl S. Justice, Ching Yang, John David Spencer, Brian Becknell and Santiago Partida-Sanchez
    JASN January 2021, 32 (1) 69-85; DOI: https://doi.org/10.1681/ASN.2020030362
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  • Transcriptomes of Major Proximal Tubule Cell Culture Models
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    Transcriptomes of Major Proximal Tubule Cell Culture Models
    Syed J. Khundmiri, Lihe Chen, Eleanor D. Lederer, Chin-Rang Yang and Mark A. Knepper
    JASN January 2021, 32 (1) 86-97; DOI: https://doi.org/10.1681/ASN.2020010009
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  • Humanized C3 Mouse: A Novel Accelerated Model of C3 Glomerulopathy
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    Humanized C3 Mouse: A Novel Accelerated Model of C3 Glomerulopathy
    Kishor Devalaraja-Narashimha, Karoline Meagher, Yifan Luo, Cong Huang, Theodore Kaplan, Anantharaman Muthuswamy, Gabor Halasz, Sarah Casanova, John O’Brien, Rebecca Peyser Boiarsky, John McWhirter, Hans Gartner, Yu Bai, Scott MacDonnell, Chien Liu, Ying Hu, Adrianna Latuszek, Yi Wei, Srinivasa Prasad, Tammy Huang, George Yancopoulos, Andrew Murphy, William Olson, Brian Zambrowicz, Lynn Macdonald and Lori G. Morton
    JASN January 2021, 32 (1) 99-114; DOI: https://doi.org/10.1681/ASN.2020050698
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Clinical Epidemiology

  • Association of Multiple Plasma Biomarker Concentrations with Progression of Prevalent Diabetic Kidney Disease: Findings from the Chronic Renal Insufficiency Cohort (CRIC) Study
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    Association of Multiple Plasma Biomarker Concentrations with Progression of Prevalent Diabetic Kidney Disease: Findings from the Chronic Renal Insufficiency Cohort (CRIC) Study
    Sarah J. Schrauben, Haochang Shou, Xiaoming Zhang, Amanda Hyre Anderson, Joseph V. Bonventre, Jing Chen, Steven Coca, Susan L. Furth, Jason H. Greenberg, Orlando M. Gutierrez, Joachim H. Ix, James P. Lash, Chirag R. Parikh, Casey M. Rebholz, Venkata Sabbisetti, Mark J. Sarnak, Michael G. Shlipak, Sushrut S. Waikar, Paul L. Kimmel, Ramachandran S. Vasan, Harold I. Feldman, Jeffrey R. Schelling and on behalf of the CKD Biomarkers Consortium and the Chronic Renal Insufficiency Cohort (CRIC) Study Investigators
    JASN January 2021, 32 (1) 115-126; DOI: https://doi.org/10.1681/ASN.2020040487
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  • Conventional and Genetic Evidence on the Association between Adiposity and CKD
    Open Access
    Conventional and Genetic Evidence on the Association between Adiposity and CKD
    Pengfei Zhu, William G. Herrington, Richard Haynes, Jonathan Emberson, Martin J. Landray, Cathie L.M. Sudlow, Mark Woodward, Colin Baigent, Sarah Lewington and Natalie Staplin
    JASN January 2021, 32 (1) 127-137; DOI: https://doi.org/10.1681/ASN.2020050679
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  • The Relationship between AKI and CKD in Patients with Type 2 Diabetes: An Observational Cohort Study
    Open Access
    The Relationship between AKI and CKD in Patients with Type 2 Diabetes: An Observational Cohort Study
    Simona Hapca, Moneeza K. Siddiqui, Ryan S.Y. Kwan, Michelle Lim, Shona Matthew, Alex S.F. Doney, Ewan R. Pearson, Colin N.A. Palmer, Samira Bell and on behalf of the BEAt-DKD Consortium
    JASN January 2021, 32 (1) 138-150; DOI: https://doi.org/10.1681/ASN.2020030323
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Clinical Research

  • AKI in Hospitalized Patients with COVID-19
    Open Access
    AKI in Hospitalized Patients with COVID-19
    Lili Chan, Kumardeep Chaudhary, Aparna Saha, Kinsuk Chauhan, Akhil Vaid, Shan Zhao, Ishan Paranjpe, Sulaiman Somani, Felix Richter, Riccardo Miotto, Anuradha Lala, Arash Kia, Prem Timsina, Li Li, Robert Freeman, Rong Chen, Jagat Narula, Allan C. Just, Carol Horowitz, Zahi Fayad, Carlos Cordon-Cardo, Eric Schadt, Matthew A. Levin, David L. Reich, Valentin Fuster, Barbara Murphy, John C. He, Alexander W. Charney, Erwin P. Böttinger, Benjamin S. Glicksberg, Steven G. Coca, Girish N. Nadkarni and on behalf of the Mount Sinai COVID Informatics Center (MSCIC)*
    JASN January 2021, 32 (1) 151-160; DOI: https://doi.org/10.1681/ASN.2020050615
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  • AKI Treated with Renal Replacement Therapy in Critically Ill Patients with COVID-19
    Open Access
    AKI Treated with Renal Replacement Therapy in Critically Ill Patients with COVID-19
    Shruti Gupta, Steven G. Coca, Lili Chan, Michal L. Melamed, Samantha K. Brenner, Salim S. Hayek, Anne Sutherland, Sonika Puri, Anand Srivastava, Amanda Leonberg-Yoo, Alexandre M. Shehata, Jennifer E. Flythe, Arash Rashidi, Edward J. Schenck, Nitender Goyal, S. Susan Hedayati, Rajany Dy, Anip Bansal, Ambarish Athavale, H. Bryant Nguyen, Anitha Vijayan, David M. Charytan, Carl E. Schulze, Min J. Joo, Allon N. Friedman, Jingjing Zhang, Marie Anne Sosa, Eric Judd, Juan Carlos Q. Velez, Mary Mallappallil, Roberta E. Redfern, Amar D. Bansal, Javier A. Neyra, Kathleen D. Liu, Amanda D. Renaghan, Marta Christov, Miklos Z. Molnar, Shreyak Sharma, Omer Kamal, Jeffery Owusu Boateng, Samuel A.P. Short, Andrew J. Admon, Meghan E. Sise, Wei Wang, Chirag R. Parikh, David E. Leaf and and the STOP-COVID Investigators
    JASN January 2021, 32 (1) 161-176; DOI: https://doi.org/10.1681/ASN.2020060897
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  • Normalization of Cerebral Blood Flow, Neurochemicals, and White Matter Integrity after Kidney Transplantation
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    Normalization of Cerebral Blood Flow, Neurochemicals, and White Matter Integrity after Kidney Transplantation
    Rebecca J. Lepping, Robert N. Montgomery, Palash Sharma, Jonathan D. Mahnken, Eric D. Vidoni, In-Young Choi, Mark J. Sarnak, William M. Brooks, Jeffrey M. Burns and Aditi Gupta
    JASN January 2021, 32 (1) 177-187; DOI: https://doi.org/10.1681/ASN.2020050584
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    Differences in 25-Hydroxyvitamin D Clearance by eGFR and Race: A Pharmacokinetic Study
    Simon Hsu, Leila R. Zelnick, Yvonne S. Lin, Cora M. Best, Bryan Kestenbaum, Kenneth E. Thummel, Lynn M. Rose, Andrew N. Hoofnagle and Ian H. de Boer
    JASN January 2021, 32 (1) 188-198; DOI: https://doi.org/10.1681/ASN.2020050625
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  • Comparison of the Efficacy and Safety of Tacrolimus and Low-Dose Corticosteroid with High-Dose Corticosteroid for Minimal Change Nephrotic Syndrome in Adults
    Open Access
    Comparison of the Efficacy and Safety of Tacrolimus and Low-Dose Corticosteroid with High-Dose Corticosteroid for Minimal Change Nephrotic Syndrome in Adults
    Ho Jun Chin, Dong-Wan Chae, Yong Chul Kim, Won Suk An, ChunGyoo Ihm, Dong-Chan Jin, Sung Gyun Kim, Yong-Lim Kim, Yong-Soo Kim, Yoon-Goo Kim, Ho Seok Koo, Jung Eun Lee, Kang Wook Lee, Jieun Oh, Jung Hwan Park, Hongsi Jiang, Hyuncheol Lee and Sang Koo Lee
    JASN January 2021, 32 (1) 199-210; DOI: https://doi.org/10.1681/ASN.2019050546
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  • Ziltivekimab for Treatment of Anemia of Inflammation in Patients on Hemodialysis: Results from a Phase 1/2 Multicenter, Randomized, Double-Blind, Placebo-Controlled Trial
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    Ziltivekimab for Treatment of Anemia of Inflammation in Patients on Hemodialysis: Results from a Phase 1/2 Multicenter, Randomized, Double-Blind, Placebo-Controlled Trial
    Pablo E. Pergola, Matt Devalaraja, Steven Fishbane, Michel Chonchol, Vandana S. Mathur, Mark T. Smith, Larry Lo, Kurt Herzog, Rahul Kakkar and Michael H. Davidson
    JASN January 2021, 32 (1) 211-222; DOI: https://doi.org/10.1681/ASN.2020050595
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  • Biallelic Pathogenic <em>GFRA1</em> Variants Cause Autosomal Recessive Bilateral Renal Agenesis
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    Biallelic Pathogenic GFRA1 Variants Cause Autosomal Recessive Bilateral Renal Agenesis
    Veronica Arora, Suliman Khan, Ayman W. El-Hattab, Ratna Dua Puri, Maria Eugenia Rocha, Rijad Merdzanic, Omid Paknia, Christian Beetz, Arndt Rolfs, Aida M. Bertoli-Avella, Peter Bauer and Ishwar C. Verma
    JASN January 2021, 32 (1) 223-228; DOI: https://doi.org/10.1681/ASN.2020040478
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  • Intracellular Phosphate and ATP Depletion Measured by Magnetic Resonance Spectroscopy in Patients Receiving Maintenance Hemodialysis
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    Intracellular Phosphate and ATP Depletion Measured by Magnetic Resonance Spectroscopy in Patients Receiving Maintenance Hemodialysis
    Guillaume Chazot, Sandrine Lemoine, Gabriel Kocevar, Emilie Kalbacher, Dominique Sappey-Marinier, Olivier Rouvière and Laurent Juillard
    JASN January 2021, 32 (1) 229-237; DOI: https://doi.org/10.1681/ASN.2020050716
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Meta-Analysis

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    Modifiable Lifestyle Factors for Primary Prevention of CKD: A Systematic Review and Meta-Analysis
    Jaimon T. Kelly, Guobin Su, La Zhang, Xindong Qin, Skye Marshall, Ailema González-Ortiz, Catherine M. Clase, Katrina L. Campbell, Hong Xu and Juan-Jesus Carrero
    JASN January 2021, 32 (1) 239-253; DOI: https://doi.org/10.1681/ASN.2020030384
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Letters to the Editor

  • Open Access
    Post-Mortem Diagnostics in COVID-19 AKI, More Often but Timely
    Jan G. Zijlstra, Matijs van Meurs and Jill Moser
    JASN January 2021, 32 (1) 255; DOI: https://doi.org/10.1681/ASN.2020091263
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  • Open Access
    Authors’ Reply
    Jordan L. Rosenstock and Vanesa Bijol
    JASN January 2021, 32 (1) 255-256; DOI: https://doi.org/10.1681/ASN.2020101479
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    Complexities of eGFRs in a Study of Glomerular Physiology
    Robert W. Steiner
    JASN January 2021, 32 (1) 256-257; DOI: https://doi.org/10.1681/ASN.2020091364
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    Authors’ Reply
    Didier Collard, Lennart van de Velde, Liffert Vogt and Bert-Jan H. van den Born
    JASN January 2021, 32 (1) 257-258; DOI: https://doi.org/10.1681/ASN.2020101478
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Journal of the American Society of Nephrology: 32 (1)
Journal of the American Society of Nephrology
Vol. 32, Issue 1
January 2021
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  • Remdesivir in Patients with Acute or Chronic Kidney Disease and COVID-19
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