On the cover: During chronic vascular rejection, NK cells can be activated either by donor-specific antibodies (DSA) or because of the lack of expression of recipient's HLA class I on the graft (missing self). In the present translational study, we demonstrated that missing self combines with non-complement fixing DSA to accelerate graft loss. Here is depicted the schematic representation of human NK cells/endothelial cells co-cultures in which the viability of endothelial cells was assessed by real-time impedance measurement. Figure provided by Alice Koenig.