Journal of the American Society of Nephrology: 32 (4)

April 2021; Volume 32,Issue 4

This Month's Highlights

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This Month's Highlights
JASN April 2021, 32 (4) i; DOI: https://doi.org/10.1681/ASN.2021020241

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Up Front Matters

Editorials
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  Automated Quantification of Chronic Changes in the Kidney Biopsy: Another Step in the Right Direction
  Jeffrey B. Hodgin and Laura H. Mariani
  
  JASN April 2021, 32 (4) 767-768; DOI: https://doi.org/10.1681/ASN.2021020240
  
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  Me Or Your Own Eyes: RNA-Seq and the Kidney
  David H. Ellison
  
  JASN April 2021, 32 (4) 768-771; DOI: https://doi.org/10.1681/ASN.2021010017
  
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  QALYs, DALYs and Now PALYs: Strengthening the Argument for Prevention of CKD
  Mark Canney and Adeera Levin
  
  JASN April 2021, 32 (4) 771-773; DOI: https://doi.org/10.1681/ASN.2021020208
  
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Perspective
- Open Access
  Passage of the Comprehensive Immunosuppressive Drug Coverage for Kidney Transplant Patients Act—a Chance to Celebrate and Reflect
  John S. Gill, Richard N. Formica and Barbara Murphy
  
  JASN April 2021, 32 (4) 774-776; DOI: https://doi.org/10.1681/ASN.2020121811
  
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Review
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  Management of Obesity in Adults with CKD
  Allon N. Friedman, Lee M. Kaplan, Carel W. le Roux and Philip R. Schauer
  
  JASN April 2021, 32 (4) 777-790; DOI: https://doi.org/10.1681/ASN.2020101472
  
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Research Letter

Open Access
Comparative Analysis of SARS-CoV-2 Reproduction Rates in the Dialysis and General Populations
Alhaji Cherif, Joanna L. Willetts, Len Usvyat, Yuedong Wang and Peter Kotanko

JASN April 2021, 32 (4) 791-794; DOI: https://doi.org/10.1681/ASN.2020121691

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Rapid Communications

Open Access
A Novel Soluble ACE2 Variant with Prolonged Duration of Action Neutralizes SARS-CoV-2 Infection in Human Kidney Organoids
Jan Wysocki, Minghao Ye, Luise Hassler, Ashwani Kumar Gupta, Yuguo Wang, Vlad Nicoleascu, Glenn Randall, Jason A. Wertheim and Daniel Batlle

JASN April 2021, 32 (4) 795-803; DOI: https://doi.org/10.1681/ASN.2020101537

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Basic Research

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Copy Number Variant Analysis and Genome-wide Association Study Identify Loci with Large Effect for Vesicoureteral Reflux
Miguel Verbitsky, Priya Krithivasan, Ekaterina Batourina, Atlas Khan, Sarah E. Graham, Maddalena Marasà, Hyunwoo Kim, Tze Y. Lim, Patricia L. Weng, Elena Sánchez-Rodríguez, Adele Mitrotti, Dina F. Ahram, Francesca Zanoni, David A. Fasel, Rik Westland, Matthew G. Sampson, Jun Y. Zhang, Monica Bodria, Byum Hee Kil, Shirlee Shril, Loreto Gesualdo, Fabio Torri, Francesco Scolari, Claudia Izzi, Joanna A.E. van Wijk, Marijan Saraga, Domenico Santoro, Giovanni Conti, David E. Barton, Mark G. Dobson, Prem Puri, Susan L. Furth, Bradley A. Warady, Isabella Pisani, Enrico Fiaccadori, Landino Allegri, Maria Ludovica Degl'Innocenti, Giorgio Piaggio, Shumyle Alam, Maddalena Gigante, Gianluigi Zaza, Pasquale Esposito, Fangming Lin, Ana Cristina Simões-e-Silva, Andrzej Brodkiewicz, Dorota Drozdz, Katarzyna Zachwieja, Monika Miklaszewska, Maria Szczepanska, Piotr Adamczyk, Marcin Tkaczyk, Daria Tomczyk, Przemyslaw Sikora, Malgorzata Mizerska-Wasiak, Grazyna Krzemien, Agnieszka Szmigielska, Marcin Zaniew, Vladimir J. Lozanovski, Zoran Gucev, Iuliana Ionita-Laza, Ian B. Stanaway, David R. Crosslin, Craig S. Wong, Friedhelm Hildebrandt, Jonathan Barasch, Eimear E. Kenny, Ruth J.F. Loos, Brynn Levy, Gian Marco Ghiggeri, Hakon Hakonarson, Anna Latos-Bieleńska, Anna Materna-Kiryluk, John M. Darlow, Velibor Tasic, Cristen Willer, Krzysztof Kiryluk, Simone Sanna-Cherchi, Cathy L. Mendelsohn and Ali G. Gharavi

JASN April 2021, 32 (4) 805-820; DOI: https://doi.org/10.1681/ASN.2020050681

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mtor Haploinsufficiency Ameliorates Renal Cysts and Cilia Abnormality in Adult Zebrafish tmem67 Mutants
Ping Zhu, Qi Qiu, Peter C. Harris, Xiaolei Xu and Xueying Lin

JASN April 2021, 32 (4) 822-836; DOI: https://doi.org/10.1681/ASN.2020070991

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Automated Computational Detection of Interstitial Fibrosis, Tubular Atrophy, and Glomerulosclerosis
Brandon Ginley, Kuang-Yu Jen, Seung Seok Han, Luís Rodrigues, Sanjay Jain, Agnes B. Fogo, Jonathan Zuckerman, Vighnesh Walavalkar, Jeffrey C. Miecznikowski, Yumeng Wen, Felicia Yen, Donghwan Yun, Kyung Chul Moon, Avi Rosenberg, Chirag Parikh and Pinaki Sarder

JASN April 2021, 32 (4) 837-850; DOI: https://doi.org/10.1681/ASN.2020050652

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NBCn1 Increases NH₄⁺ Reabsorption Across Thick Ascending Limbs, the Capacity for Urinary NH₄⁺ Excretion, and Early Recovery from Metabolic Acidosis
Jeppe S. M. Olsen, Samuel Svendsen, Peder Berg, Vibeke S. Dam, Mads V. Sorensen, Vladimir V. Matchkov, Jens Leipziger and Ebbe Boedtkjer

JASN April 2021, 32 (4) 852-865; DOI: https://doi.org/10.1681/ASN.2019060613

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1α,25-Dihydroxyvitamin D₃ Encapsulated in Nanoparticles Prevents Venous Neointimal Hyperplasia and Stenosis in Porcine Arteriovenous Fistulas
Avishek K. Singh, Chuanqi Cai, Sreenivasulu Kilari, Chenglei Zhao, Michael L. Simeon, Edwin Takahashi, Elazer R. Edelman, Hyunjoon (Joon) Kong, Thanila Macedo, Ravinder J. Singh, Matthew W. Urban, Rajiv Kumar and Sanjay Misra

JASN April 2021, 32 (4) 866-885; DOI: https://doi.org/10.1681/ASN.2020060832

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Targeted Single-Cell RNA-seq Identifies Minority Cell Types of Kidney Distal Nephron
Lihe Chen, Chun-Lin Chou and Mark A. Knepper

JASN April 2021, 32 (4) 886-896; DOI: https://doi.org/10.1681/ASN.2020101407

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A Comprehensive Map of mRNAs and Their Isoforms across All 14 Renal Tubule Segments of Mouse
Lihe Chen, Chun-Lin Chou and Mark A. Knepper

JASN April 2021, 32 (4) 897-912; DOI: https://doi.org/10.1681/ASN.2020101406

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Clinical Epidemiology

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Failure to Advance Access to Kidney Transplantation over Two Decades in the United States
Jesse D. Schold, Sumit Mohan, Anne Huml, Laura D. Buccini, John R. Sedor, Joshua J. Augustine and Emilio D. Poggio

JASN April 2021, 32 (4) 913-926; DOI: https://doi.org/10.1681/ASN.2020060888

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Cardiovascular Risk Based on ASCVD and KDIGO Categories in Chinese Adults: A Nationwide, Population-Based, Prospective Cohort Study
Yu Xu, Mian Li, Guijun Qin, Jieli Lu, Li Yan, Min Xu, Tiange Wang, Zhiyun Zhao, Meng Dai, Di Zhang, Qin Wan, Yanan Huo, Lulu Chen, Lixin Shi, Ruying Hu, Xulei Tang, Qing Su, Xuefeng Yu, Yingfen Qin, Gang Chen, Zhengnan Gao, Guixia Wang, Feixia Shen, Zuojie Luo, Li Chen, Yuhong Chen, Yinfei Zhang, Chao Liu, Youmin Wang, Shengli Wu, Tao Yang, Qiang Li, Yufang Bi, Jiajun Zhao, Yiming Mu, Weiqing Wang, Guang Ning and for the China Cardiometabolic Disease and Cancer Cohort (4C) Study Group

JASN April 2021, 32 (4) 927-937; DOI: https://doi.org/10.1681/ASN.2020060856

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The Preventable Productivity Burden of Kidney Disease in Australia
Feby Savira, Zanfina Ademi, Bing H. Wang, Andrew R. Kompa, Alice J. Owen, Danny Liew and Ella Zomer

JASN April 2021, 32 (4) 938-949; DOI: https://doi.org/10.1681/ASN.2020081148

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Laxative Use and Risk of Dyskalemia in Patients with Advanced CKD Transitioning to Dialysis
Keiichi Sumida, Ankur A. Dashputre, Praveen K. Potukuchi, Fridtjof Thomas, Yoshitsugu Obi, Miklos Z. Molnar, Justin D. Gatwood, Elani Streja, Kamyar Kalantar-Zadeh and Csaba P. Kovesdy

JASN April 2021, 32 (4) 950-959; DOI: https://doi.org/10.1681/ASN.2020081120

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Clinical Research

Open Access
Risks of AKI and Major Adverse Clinical Outcomes in Patients with Severe Acute Respiratory Syndrome or Coronavirus Disease 2019
Jeremy Yuen-Chun Teoh, Terry Cheuk-Fung Yip, Grace Chung-Yan Lui, Vincent Wai-Sun Wong, Viola Chi-Ying Chow, Tracy Hang-Yee Ho, Timothy Chun-Man Li, Yee-Kit Tse, Peter Ka-Fung Chiu, Chi-Fai Ng, David Shu-Cheong Hui, Henry Lik-Yuen Chan, Cheuk-Chun Szeto and Grace Lai-Hung Wong

JASN April 2021, 32 (4) 961-971; DOI: https://doi.org/10.1681/ASN.2020071097

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Rituximab or Cyclophosphamide in the Treatment of Membranous Nephropathy: The RI-CYCLO Randomized Trial
Francesco Scolari, Elisa Delbarba, Domenico Santoro, Loreto Gesualdo, Antonello Pani, Nadia Dallera, Laila-Yasmin Mani, Marisa Santostefano, Sandro Feriozzi, Marco Quaglia, Giuliano Boscutti, Angelo Ferrantelli, Carmelita Marcantoni, Patrizia Passerini, Riccardo Magistroni, Federico Alberici, Gian Marco Ghiggeri, Claudio Ponticelli, Pietro Ravani and for the RI-CYCLO Investigators

JASN April 2021, 32 (4) 972-982; DOI: https://doi.org/10.1681/ASN.2020071091

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Kidney Function after Treatment for Childhood Cancer: A Report from the St. Jude Lifetime Cohort Study
Daniel M. Green, Mingjuan Wang, Matthew Krasin, DeoKumar Srivastava, Songul Onder, Dennis W. Jay, Kirsten K. Ness, William Greene, Jennifer Q. Lanctot, Kyla C. Shelton, Liang Zhu, Daniel A. Mulrooney, Matthew J. Ehrhardt, Andrew M. Davidoff, Leslie L. Robison and Melissa M. Hudson

JASN April 2021, 32 (4) 983-993; DOI: https://doi.org/10.1681/ASN.2020060849

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Open Access
Discovery and Validation of a Urinary Exosome mRNA Signature for the Diagnosis of Human Kidney Transplant Rejection
Rania El Fekih, James Hurley, Vasisht Tadigotla, Areej Alghamdi, Anand Srivastava, Christine Coticchia, John Choi, Hazim Allos, Karim Yatim, Juliano Alhaddad, Siawosh Eskandari, Philip Chu, Albana B. Mihali, Isadora T. Lape, Mauricio P. Lima Filho, Bruno T. Aoyama, Anil Chandraker, Kassem Safa, James F. Markmann, Leonardo V. Riella, Richard N. Formica, Johan Skog and Jamil R. Azzi

JASN April 2021, 32 (4) 994-1004; DOI: https://doi.org/10.1681/ASN.2020060850

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Letters to the Editor

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Roxadustat for Renal Anemia in ESRD from PKD Patients: Is It Safe Enough?
Fei Liu, Jingjing Wang, Qing Ye, Haidong Fu and Jianhua Mao

JASN April 2021, 32 (4) 1005; DOI: https://doi.org/10.1681/ASN.2020111664

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Authors’ Reply
Tadao Akizawa, Manabu Iwasaki, Yusuke Yamaguchi, Yoshikatsu Majikawa and Michael Reusch

JASN April 2021, 32 (4) 1005-1007; DOI: https://doi.org/10.1681/ASN.2021010051

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Table of Contents

This Month's Highlights

Up Front Matters

Editorials

Perspective

Review

Research Letter

Rapid Communications

Basic Research

Clinical Epidemiology

Clinical Research

Letters to the Editor

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