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Table of Contents

April 2022; Volume 33,Issue 4

Looking for COVID information? All ASN Journal COVID articles are in the COVID-19 Research Collection or the COVID-19 In Context Collection. All articles are free.​

This Month’s Highlights

  • You have accessRestricted Access
    This Month's Highlights
    JASN April 2022, 33 (4) i; DOI: https://doi.org/10.1681/ASN.2022020203
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Up Front Matters

  • Editorials

    • You have accessRestricted Access
      New Insights into the Pivotal Roles of Claudins in Proximal Tubule Electrolyte Reabsorption
      Peter S. Aronson
      JASN April 2022, 33 (4) 659-661; DOI: https://doi.org/10.1681/ASN.2022020157
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    • You have accessRestricted Access
      Endocytosis Begins inside the Cell
      Andrew Beenken
      JASN April 2022, 33 (4) 661-662; DOI: https://doi.org/10.1681/ASN.2022020155
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    • You have accessRestricted Access
      The Search for the Perfect Agent for Anemia Management in Chronic Kidney Disease
      Francesco Locatelli and Lucia Del Vecchio
      JASN April 2022, 33 (4) 662-664; DOI: https://doi.org/10.1681/ASN.2022020173
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  • Perspectives

    • Open Access
      Premature Death in Kidney Transplant Recipients: The Time for Trials is Now
      Amanda J. Vinson, Sunita Singh, Steven Chadban, David Cherney, Osama Gaber, John S. Gill, Erika Helgeson, Charles A. Herzog, Meg Jardine, Vivekanand Jha, Bertram L. Kasiske, Roslyn B. Mannon, Erin D. Michos, Amy K. Mottl, Kristin Newby, Prabir Roy-Chaudhury, Deirdre Sawinski, Adnan Sharif, Vikas S. Sridhar, Katherine R. Tuttle, David M. Vock and Arthur Matas
      JASN April 2022, 33 (4) 665-673; DOI: https://doi.org/10.1681/ASN.2021111517
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    • Open Access
      The Non-Inferiority Complex: What Do Non-Inferiority Trials Tell Us?
      Magdalene M. Assimon, Gary R. Cutter and Joanne M. Bargman
      JASN April 2022, 33 (4) 674-676; DOI: https://doi.org/10.1681/ASN.2021050681
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Rapid Communications

  • The Impact of Vaccination on Incidence and Outcomes of SARS-CoV-2 Infection in Patients with Kidney Failure in Scotland
    Open Access
    The Impact of Vaccination on Incidence and Outcomes of SARS-CoV-2 Infection in Patients with Kidney Failure in Scotland
    Samira Bell, Jacqueline Campbell, Emilie Lambourg, Chrissie Watters, Martin O’Neil, Alison Almond, Katharine Buck, Edward J. Carr, Laura Clark, Zoe Cousland, Mark Findlay, Nicola Joss, Wendy Metcalfe, Michaela Petrie, Elaine Spalding, Jamie P. Traynor, Vinod Sanu, Peter Thomson, Shona Methven and Patrick B. Mark
    JASN April 2022, 33 (4) 677-686; DOI: https://doi.org/10.1681/ASN.2022010046
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  • Open Access
    Comparative Effectiveness of mRNA-based BNT162b2 Vaccine versus Adenovirus Vector–Based Ad26.COV2.S Vaccine for the Prevention of COVID-19 among Dialysis Patients
    Steven M. Brunelli, Scott Sibbel, Steph Karpinski, Gilbert Marlowe, Adam G. Walker, Jeffrey Giullian, David Van Wyck, Tara Kelley, Rachael Lazar, Meredith L. Zywno, Jeffrey J. Connaire, Amy Young and Francesca Tentori
    JASN April 2022, 33 (4) 688-697; DOI: https://doi.org/10.1681/ASN.2021101395
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Basic Research

  • Claudin-10a Deficiency Shifts Proximal Tubular Cl<sup>-</sup> Permeability to Cation Selectivity <em>via</em> Claudin-2 Redistribution
    You have accessRestricted Access
    Claudin-10a Deficiency Shifts Proximal Tubular Cl- Permeability to Cation Selectivity via Claudin-2 Redistribution
    Tilman Breiderhoff, Nina Himmerkus, Luca Meoli, Anja Fromm, Sebastian Sewerin, Natalia Kriuchkova, Oliver Nagel, Yury Ladilov, Susanne M. Krug, Catarina Quintanova, Meike Stumpp, Dieter Garbe-Schönberg, Ulrike Westernströer, Cosima Merkel, Merle Annette Brinkhus, Janine Altmüller, Michal R. Schweiger, Dominik Müller, Kerim Mutig, Markus Morawski, Jan Halbritter, Susanne Milatz, Markus Bleich and Dorothee Günzel
    JASN April 2022, 33 (4) 699-717; DOI: https://doi.org/10.1681/ASN.2021030286
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  • A Neutralizing IL-11 Antibody Improves Renal Function and Increases Lifespan in a Mouse Model of Alport Syndrome
    Open Access
    A Neutralizing IL-11 Antibody Improves Renal Function and Increases Lifespan in a Mouse Model of Alport Syndrome
    Anissa A. Widjaja, Shamini G. Shekeran, Eleonora Adami, Joyce G Wei Ting, Jessie Tan, Sivakumar Viswanathan, Sze Yun Lim, Puay Hoon Tan, Norbert Hübner, Thomas Coffman and Stuart A. Cook
    JASN April 2022, 33 (4) 718-730; DOI: https://doi.org/10.1681/ASN.2021040577
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  • A Founder Mutation in <em>EHD1</em> Presents with Tubular Proteinuria and Deafness
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    A Founder Mutation in EHD1 Presents with Tubular Proteinuria and Deafness
    Naomi Issler, Sara Afonso, Irith Weissman, Katrin Jordan, Alberto Cebrian-Serrano, Katrin Meindl, Eileen Dahlke, Konstantin Tziridis, Guanhua Yan, José M. Robles-López, Lydia Tabernero, Vaksha Patel, Anne Kesselheim, Enriko D. Klootwijk, Horia C. Stanescu, Simona Dumitriu, Daniela Iancu, Mehmet Tekman, Monika Mozere, Graciana Jaureguiberry, Priya Outtandy, Claire Russell, Anna-Lena Forst, Christina Sterner, Elena-Sofia Heinl, Helga Othmen, Ines Tegtmeier, Markus Reichold, Ina Maria Schiessl, Katharina Limm, Peter Oefner, Ralph Witzgall, Lifei Fu, Franziska Theilig, Achim Schilling, Efrat Shuster Biton, Limor Kalfon, Ayalla Fedida, Elite Arnon-Sheleg, Ofer Ben Izhak, Daniella Magen, Yair Anikster, Holger Schulze, Christine Ziegler, Martin Lowe, Benjamin Davies, Detlef Böckenhauer, Robert Kleta, Tzipora C. Falik Zaccai and Richard Warth
    JASN April 2022, 33 (4) 732-745; DOI: https://doi.org/10.1681/ASN.2021101312
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  • A Comprehensive Immune Cell Atlas of Cystic Kidney Disease Reveals the Involvement of Adaptive Immune Cells in Injury-Mediated Cyst Progression in Mice
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    A Comprehensive Immune Cell Atlas of Cystic Kidney Disease Reveals the Involvement of Adaptive Immune Cells in Injury-Mediated Cyst Progression in Mice
    Cheng J. Song, Zhang Li, Ummey Khalecha Bintha Ahmed, Sarah J. Bland, Alex Yashchenko, Shanrun Liu, Ernald J. Aloria, Jeremie M. Lever, Nancy M. Gonzalez, Marisa A. Bickel, Cory B. Giles, Constantin Georgescu, Jonathan D. Wren, Mark L. Lang, Etty N. Benveniste, Laurie E. Harrington, Leo Tsiokas, James F. George, Kenneth L. Jones, David K. Crossman, Anupam Agarwal, Michal Mrug, Bradley K. Yoder, Katharina Hopp and Kurt A. Zimmerman
    JASN April 2022, 33 (4) 747-768; DOI: https://doi.org/10.1681/ASN.2021030278
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  • Lipopolysaccharide Pretreatment Prevents Medullary Vascular Congestion following Renal Ischemia by Limiting Early Reperfusion of the Medullary Circulation
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    Lipopolysaccharide Pretreatment Prevents Medullary Vascular Congestion following Renal Ischemia by Limiting Early Reperfusion of the Medullary Circulation
    Sarah R. McLarnon, Katie Wilson, Bansari Patel, Jingping Sun, Christina L. Sartain, Christopher D. Mejias, Jacqueline B. Musall, Jennifer C. Sullivan, Qingqing Wei, Jian-Kang Chen, Kelly A. Hyndman, Brendan Marshall, Haichun Yang, Agnes B. Fogo and Paul M. O’Connor
    JASN April 2022, 33 (4) 769-785; DOI: https://doi.org/10.1681/ASN.2021081089
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  • α-Parvin Defines a Specific Integrin Adhesome to Maintain the Glomerular Filtration Barrier
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    α-Parvin Defines a Specific Integrin Adhesome to Maintain the Glomerular Filtration Barrier
    Manuel Rogg, Jasmin I. Maier, Clara Van Wymersch, Martin Helmstädter, Alena Sammarco, Maja Lindenmeyer, Paulina Zareba, Eloi Montanez, Gerd Walz, Martin Werner, Nicole Endlich, Thomas Benzing, Tobias B. Huber and Christoph Schell
    JASN April 2022, 33 (4) 786-808; DOI: https://doi.org/10.1681/ASN.2021101319
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  • Decreased Renal Gluconeogenesis Is a Hallmark of Chronic Kidney Disease
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    Decreased Renal Gluconeogenesis Is a Hallmark of Chronic Kidney Disease
    Thomas Verissimo, Anna Faivre, Anna Rinaldi, Maja Lindenmeyer, Vasiliki Delitsikou, Christelle Veyrat-Durebex, Carolyn Heckenmeyer, Marylise Fernandez, Lena Berchtold, Delal Dalga, Clemens Cohen, Maarten Naesens, Sven-Erik Ricksten, Pierre-Yves Martin, Jérôme Pugin, Franck Merlier, Karsten Haupt, Joseph M. Rutkowski, Solange Moll, Pietro E. Cippà, David Legouis and Sophie de Seigneux
    JASN April 2022, 33 (4) 810-827; DOI: https://doi.org/10.1681/ASN.2021050680
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Clinical Research

  • Endopeptidase Cleavage of Anti-Glomerular Basement Membrane Antibodies <em>in vivo</em> in Severe Kidney Disease: An Open-Label Phase 2a Study
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    Endopeptidase Cleavage of Anti-Glomerular Basement Membrane Antibodies in vivo in Severe Kidney Disease: An Open-Label Phase 2a Study
    Fredrik Uhlin, Wladimir Szpirt, Andreas Kronbichler, Annette Bruchfeld, Inga Soveri, Lionel Rostaing, Eric Daugas, Arnaud Lionet, Nassim Kamar, Cédric Rafat, Marek Mysliveček, Vladimír Tesař, Anders Fernström, Christian Kjellman, Charlotte Elfving, Stephen McAdoo, Johan Mölne, Ingeborg Bajema, Elisabeth Sonesson and Mårten Segelmark
    JASN April 2022, 33 (4) 829-838; DOI: https://doi.org/10.1681/ASN.2021111460
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  • Vaccine Effectiveness Against SARS-CoV-2 Infection and Severe Outcomes in the Maintenance Dialysis Population in Ontario, Canada
    Open Access
    Vaccine Effectiveness Against SARS-CoV-2 Infection and Severe Outcomes in the Maintenance Dialysis Population in Ontario, Canada
    Matthew J. Oliver, Doneal Thomas, Shabnam Balamchi, Jane Ip, Kyla Naylor, Stephanie N. Dixon, Eric McArthur, Jeff Kwong, Jeffrey Perl, Mohammad Atiquzzaman, Joel Singer, Angie Yeung, Michelle Hladunewich, Kevin Yau, Amit X. Garg, Jerome A. Leis, Adeera Levin, Mel Krajden and Peter G. Blake
    JASN April 2022, 33 (4) 839-849; DOI: https://doi.org/10.1681/ASN.2021091262
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  • Roxadustat Versus Epoetin Alfa for Treating Anemia in Patients with Chronic Kidney Disease on Dialysis: Results from the Randomized Phase 3 ROCKIES Study
    Open Access
    Roxadustat Versus Epoetin Alfa for Treating Anemia in Patients with Chronic Kidney Disease on Dialysis: Results from the Randomized Phase 3 ROCKIES Study
    Steven Fishbane, Carol A. Pollock, Mohamed El-Shahawy, Elizabeth T. Escudero, Anjay Rastogi, Bui Pham Van, Lars Frison, Mark Houser, Maksym Pola, Dustin J. Little, Nicolas Guzman and Pablo E. Pergola
    JASN April 2022, 33 (4) 850-866; DOI: https://doi.org/10.1681/ASN.2020111638
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Letters to the Editor

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    Advanced Tertiary Lymphoid Tissues in Protocol Biopsies in Kidney Transplant Recipients: Addressing Additional Methods To Detect Intragraft B Cells
    Romy du Long, Sandrine Florquin and Jesper Kers
    JASN April 2022, 33 (4) 867; DOI: https://doi.org/10.1681/ASN.2021111509
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    Authors’ Reply: Advanced Tertiary Lymphoid Tissues in Protocol Biopsies in Kidney Transplant Recipients: Addressing Additional Methods To Detect Intragraft B Cells
    Yuki Sato, Yu Ho Lee, Keisuke Taniguchi, Takahisa Yoshikawa, Peter Boor, Jürgen Floege and Motoko Yanagita
    JASN April 2022, 33 (4) 868-869; DOI: https://doi.org/10.1681/ASN.2021121588
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  • Open Access
    SARS-CoV-2 Vaccination in Kidney Transplant Recipients: Should We Consider Intradermal Vaccination?
    Veerle Wijtvliet, Karl Martin Wissing, Daniel Abramowicz and Kristien J. Ledeganck
    JASN April 2022, 33 (4) 869-870; DOI: https://doi.org/10.1681/ASN.2021121566
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  • Open Access
    Authors’ Reply: SARS-CoV-2 Vaccination in Kidney Transplant Recipients: Should We Consider Intradermal Vaccination?
    Eva Schrezenmeier, Arne Sattler, Fabian Halleck and Klemens Budde
    JASN April 2022, 33 (4) 870-871; DOI: https://doi.org/10.1681/ASN.2022010033
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Errata

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    Correction: Megalin Blockade with Cilastatin Suppresses Drug-Induced Nephrotoxicity
    JASN April 2022, 33 (4) 872; DOI: https://doi.org/10.1681/ASN.2022010083
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Journal of the American Society of Nephrology: 33 (4)
Journal of the American Society of Nephrology
Vol. 33, Issue 4
April 2022
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