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Myoglobinuric acute renal failure in a cardiac transplant patient taking lovastatin and cyclosporine.

D S Alejandro and J Petersen
JASN August 1994, 5 (2) 153-160; DOI: https://doi.org/10.1681/ASN.V52153
D S Alejandro
Division of Nephrology, Stanford University School of Medicine, CA 94305-5114.
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J Petersen
Division of Nephrology, Stanford University School of Medicine, CA 94305-5114.
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Abstract

Acute renal failure can occur in cardiac transplant patients for a variety of reasons. A case of a patient who developed acute renal failure secondarily to drug-induced rhabdomyolysis is reported. The literature regarding acute renal failure and lovastatin and other 3-hydroxy-3-methylglutaryl-coenzyme A reductase inhibitors is reviewed. The potential mechanisms of myoglobinuria and nephrotoxicity and the therapeutic implications are discussed.

  • Copyright © 1994 by American Society of Nephrology
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Journal of the American Society of Nephrology
Vol. 5, Issue 2
1 Aug 1994
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Myoglobinuric acute renal failure in a cardiac transplant patient taking lovastatin and cyclosporine.
D S Alejandro, J Petersen
JASN Aug 1994, 5 (2) 153-160; DOI: 10.1681/ASN.V52153

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Myoglobinuric acute renal failure in a cardiac transplant patient taking lovastatin and cyclosporine.
D S Alejandro, J Petersen
JASN Aug 1994, 5 (2) 153-160; DOI: 10.1681/ASN.V52153
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Print ISSN - 1046-6673 Online ISSN - 1533-3450

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