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You have accessRestricted Access

Molecular insights into renal interstitial fibrosis.

A A Eddy
JASN December 1996, 7 (12) 2495-2508;
A A Eddy
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Article Information

vol. 7 no. 12 2495-2508
PubMed 
8989727

Published By 
American Society of Nephrology
Print ISSN 
1046-6673
Online ISSN 
1533-3450
History 
  • Published online December 1, 1996.

Copyright & Usage 
Copyright © 1996 by American Society of Nephrology

Author Information

  1. A A Eddy

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Journal of the American Society of Nephrology
Vol. 7, Issue 12
1 Dec 1996
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Molecular insights into renal interstitial fibrosis.
A A Eddy
JASN Dec 1996, 7 (12) 2495-2508;

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Molecular insights into renal interstitial fibrosis.
A A Eddy
JASN Dec 1996, 7 (12) 2495-2508;
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Cited By...

  • Severe acute dehydration in a desert rodent elicits a transcriptional response that effectively prevents kidney injury
  • Yap/Taz mediates mTORC2-stimulated fibroblast activation and kidney fibrosis
  • Depletion of CD8+ T Cells Exacerbates CD4+ T Cell-Induced Monocyte-to-Fibroblast Transition in Renal Fibrosis
  • Physiology of the Renal Interstitium
  • Vasohibin-1 deficiency enhances renal fibrosis and inflammation after unilateral ureteral obstruction
  • Rheb/mTORC1 Signaling Promotes Kidney Fibroblast Activation and Fibrosis
  • Profibrotic Effect of Interleukin-18 in HK-2 Cells Is Dependent on Stimulation of the Toll-like Receptor 4 (TLR4) Promoter and Increased TLR4 Expression
  • Response Gene to Complement 32 Is Essential for Fibroblast Activation in Renal Fibrosis
  • CXCL16 Recruits Bone Marrow-Derived Fibroblast Precursors in Renal Fibrosis
  • Role of Extracellular Matrix Renal Tubulo-interstitial Nephritis Antigen (TINag) in Cell Survival Utilizing Integrin {alpha}v{beta}3/Focal Adhesion Kinase (FAK)/Phosphatidylinositol 3-Kinase (PI3K)/Protein Kinase B-Serine/Threonine Kinase (AKT) Signaling Pathway
  • Antifibrotic activities of pirfenidone in animal models
  • Mechanisms of Tubulointerstitial Fibrosis
  • Fibroblasts in Kidney Fibrosis Emerge via Endothelial-to-Mesenchymal Transition
  • Inhibition of PDGF, VEGF and FGF signalling attenuates fibrosis
  • Advanced Oxidation Protein Products Accelerate Renal Fibrosis in a Remnant Kidney Model
  • The Role of the beta1 Subunit of the Na,K-ATPase and Its Glycosylation in Cell-Cell Adhesion
  • Heme Oxygenase-1 Protects Rat Kidney from Ureteral Obstruction via an Antiapoptotic Pathway
  • N-Acetyl-Seryl-Aspartyl-Lysyl-Proline Ameliorates the Progression of Renal Dysfunction and Fibrosis in WKY Rats with Established Anti-Glomerular Basement Membrane Nephritis
  • Pentoxifylline Attenuates Tubulointerstitial Fibrosis by Blocking Smad3/4-Activated Transcription and Profibrogenic Effects of Connective Tissue Growth Factor
  • Role of Reactive Oxygen Species in TGF-{beta}1-Induced Mitogen-Activated Protein Kinase Activation and Epithelial-Mesenchymal Transition in Renal Tubular Epithelial Cells
  • Connective Tissue Growth Factor Expressed in Tubular Epithelium Plays a Pivotal Role in Renal Fibrogenesis
  • Down-regulation of Smad7 expression by ubiquitin-dependent degradation contributes to renal fibrosis in obstructive nephropathy in mice
  • Reduction in Connective Tissue Growth Factor by Antisense Treatment Ameliorates Renal Tubulointerstitial Fibrosis
  • Evidence of Tubular Hypoxia in the Early Phase in the Remnant Kidney Model
  • Epithelial to Mesenchymal Transition in Renal Fibrogenesis: Pathologic Significance, Molecular Mechanism, and Therapeutic Intervention
  • Activin A Is a Potent Activator of Renal Interstitial Fibroblasts
  • Hepatocyte Growth Factor Modulates Matrix Metalloproteinases and Plasminogen Activator/Plasmin Proteolytic Pathways in Progressive Renal Interstitial Fibrosis
  • Glucose-Induced TGF-{beta}1 and TGF-{beta} Receptor-1 Expression in Vascular Smooth Muscle Cells Is Mediated by Protein Kinase C-{alpha}
  • Anemia Management and the Delay of Chronic Renal Failure Progression
  • Inhibition of Renal Fibrosis by Gene Transfer of Inducible Smad7 Using Ultrasound-Microbubble System in Rat UUO Model
  • Extracellular Matrix Metabolism in Diabetic Nephropathy
  • Urokinase Receptor Deficiency Accelerates Renal Fibrosis in Obstructive Nephropathy
  • Transforming Growth Factor-{beta}1 Potentiates Renal Tubular Epithelial Cell Death by a Mechanism Independent of Smad Signaling
  • Activation of Tubular Epithelial Cells in Diabetic Nephropathy
  • Hepatocyte Growth Factor Gene Therapy and Angiotensin II Blockade Synergistically Attenuate Renal Interstitial Fibrosis in Mice
  • Transforming Growth Factor-{beta} Induces Renal Epithelial Jagged-1 Expression in Fibrotic Disease
  • Smad7 Inhibits Fibrotic Effect of TGF-{beta} on Renal Tubular Epithelial Cells by Blocking Smad2 Activation
  • Regulation of Endothelial Matrix Metalloproteinase-2 by Hypoxia/Reoxygenation
  • Blockage of Tubular Epithelial to Myofibroblast Transition by Hepatocyte Growth Factor Prevents Renal Interstitial Fibrosis
  • Role of Mast Cell Tryptase in Renal Interstitial Fibrosis
  • TIMP-1 Deficiency Does Not Attenuate Interstitial Fibrosis in Obstructive Nephropathy
  • Renal Interstitial Fibrosis Is Reduced in Angiotensin II Type 1a Receptor-Deficient Mice
  • Workshop: Endothelial Cell Dysfunction Leading to Diabetic Nephropathy : Focus on Nitric Oxide
  • Acute and Chronic Renal Effects of Recombinant Human TGF-{beta}2 in the Rat
  • Regulation of Endothelial Matrix Metalloproteinase-2 by Hypoxia/Reoxygenation
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