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In vivo ANA is a fixation artifact: nucleosome-complexed antinucleosome autoantibodies bind to the cell surface and are internalized.

K Kramers, M C van Bruggen, T P Rijke-Schilder, H B Dijkman, M N Hylkema, H J Croes, J A Fransen, K J Assmann, W J Tax, R J Smeenk and J H Berden
JASN June 1996, 7 (6) 946-954;
K Kramers
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M C van Bruggen
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T P Rijke-Schilder
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H B Dijkman
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M N Hylkema
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H J Croes
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J A Fransen
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K J Assmann
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W J Tax
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R J Smeenk
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J H Berden
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Article Information

vol. 7 no. 6 946-954
PubMed 
8793805

Published By 
American Society of Nephrology
Print ISSN 
1046-6673
Online ISSN 
1533-3450
History 
  • Published online June 1, 1996.

Copyright & Usage 
Copyright © 1996 by American Society of Nephrology

Author Information

  1. K Kramers,
  2. M C van Bruggen,
  3. T P Rijke-Schilder,
  4. H B Dijkman,
  5. M N Hylkema,
  6. H J Croes,
  7. J A Fransen,
  8. K J Assmann,
  9. W J Tax,
  10. R J Smeenk and
  11. J H Berden
  1. Department of Nephrology, University Hospital, Nijmegen, The Netherlands.

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Journal of the American Society of Nephrology
Vol. 7, Issue 6
1 Jun 1996
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In vivo ANA is a fixation artifact: nucleosome-complexed antinucleosome autoantibodies bind to the cell surface and are internalized.
K Kramers, M C van Bruggen, T P Rijke-Schilder, H B Dijkman, M N Hylkema, H J Croes, J A Fransen, K J Assmann, W J Tax, R J Smeenk, J H Berden
JASN Jun 1996, 7 (6) 946-954;

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In vivo ANA is a fixation artifact: nucleosome-complexed antinucleosome autoantibodies bind to the cell surface and are internalized.
K Kramers, M C van Bruggen, T P Rijke-Schilder, H B Dijkman, M N Hylkema, H J Croes, J A Fransen, K J Assmann, W J Tax, R J Smeenk, J H Berden
JASN Jun 1996, 7 (6) 946-954;
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