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The MEK Inhibitor Trametinib Ameliorates Kidney Fibrosis by Suppressing ERK1/2 and mTORC1 Signaling
Petros Andrikopoulos, Julius Kieswich, Sabrina Pacheco, Luxme Nadarajah, Steven Michael Harwood, Caroline E. O'Riordan, Christoph Thiemermann and Muhammad M. Yaqoob

JASN December 2018, ASN.2018020209; DOI: https://doi.org/10.1681/ASN.2018020209

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Endogenous Notch Signaling in Adult Kidneys Maintains Segment-Specific Epithelial Cell Types of the Distal Tubules and Collecting Ducts to Ensure Water Homeostasis
Malini Mukherjee, Jennifer deRiso, Karla Otterpohl, Ishara Ratnayake, Divya Kota, Phil Ahrenkiel, Indra Chandrasekar and Kameswaran Surendran

JASN December 2018, ASN.2018040440; DOI: https://doi.org/10.1681/ASN.2018040440

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DNA Methyltransferase 1 Controls Nephron Progenitor Cell Renewal and Differentiation
Nicola Wanner, Julia Vornweg, Alexander Combes, Sean Wilson, Julia Plappert, Gesa Rafflenbeul, Victor G. Puelles, Raza-Ur Rahman, Timur Liwinski, Saskia Lindner, Florian Grahammer, Oliver Kretz, Mary E. Wlodek, Tania Romano, Karen M. Moritz, Melanie Boerries, Hauke Busch, Stefan Bonn, Melissa H. Little, Wibke Bechtel-Walz and Tobias B. Huber

JASN December 2018, ASN.2018070736; DOI: https://doi.org/10.1681/ASN.2018070736

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Morphological Processes of Foot Process Effacement in Puromycin Aminonucleoside Nephrosis Revealed by FIB/SEM Tomography
Koichiro Ichimura, Takayuki Miyaki, Yuto Kawasaki, Mui Kinoshita, Soichiro Kakuta and Tatsuo Sakai

JASN December 2018, ASN.2018020139; DOI: https://doi.org/10.1681/ASN.2018020139

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Genetic Analysis of 400 Patients Refines Understanding and Implicates a New Gene in Atypical Hemolytic Uremic Syndrome
Fengxiao Bu, Yuzhou Zhang, Kai Wang, Nicolo Ghiringhelli Borsa, Michael B. Jones, Amanda O. Taylor, Erika Takanami, Nicole C. Meyer, Kathy Frees, Christie P. Thomas, Carla Nester and Richard J.H. Smith

JASN December 2018, 29 (12) 2809-2819; DOI: https://doi.org/10.1681/ASN.2018070759

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A High-Throughput Screen Identifies DYRK1A Inhibitor ID-8 that Stimulates Human Kidney Tubular Epithelial Cell Proliferation
Maria B. Monteiro, Susanne Ramm, Vidya Chandrasekaran, Sarah A. Boswell, Elijah J. Weber, Kevin A. Lidberg, Edward J. Kelly and Vishal S. Vaidya

JASN December 2018, 29 (12) 2820-2833; DOI: https://doi.org/10.1681/ASN.2018040392

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Transcription Factor 21 Is Required for Branching Morphogenesis and Regulates the Gdnf-Axis in Kidney Development
Shintaro Ide, Gal Finer, Yoshiro Maezawa, Tuncer Onay, Tomokazu Souma, Rizaldy Scott, Kana Ide, Yoshihiro Akimoto, Chengjin Li, Minghao Ye, Xiangmin Zhao, Yusuke Baba, Takuya Minamizuka, Jing Jin, Minoru Takemoto, Koutaro Yokote and Susan E. Quaggin

JASN December 2018, 29 (12) 2795-2808; DOI: https://doi.org/10.1681/ASN.2017121278

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Renal COP9 Signalosome Deficiency Alters CUL3-KLHL3-WNK Signaling Pathway
Ryan J. Cornelius, Jinge Si, Catherina A. Cuevas, Jonathan W. Nelson, Brittany D.K. Gratreak, Ruggero Pardi, Chao-Ling Yang and David H. Ellison

JASN November 2018, 29 (11) 2627-2640; DOI: https://doi.org/10.1681/ASN.2018030333

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Combined Structural and Functional Imaging of the Kidney Reveals Major Axial Differences in Proximal Tubule Endocytosis
Claus D. Schuh, Marcello Polesel, Evgenia Platonova, Dominik Haenni, Alkaly Gassama, Natsuko Tokonami, Susan Ghazi, Milica Bugarski, Olivier Devuyst, Urs Ziegler and Andrew M. Hall

JASN November 2018, 29 (11) 2696-2712; DOI: https://doi.org/10.1681/ASN.2018050522

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SHROOM3-FYN Interaction Regulates Nephrin Phosphorylation and Affects Albuminuria in Allografts
Chengguo Wei, Khadija Banu, Felipe Garzon, John M. Basgen, Nimrod Philippe, Zhengzi Yi, Ruijie Liu, Jui Choudhuri, Miguel Fribourg, Tong Liu, Arun Cumpelik, Jenny Wong, Mubeen Khan, Bhaskar Das, Karen Keung, Fadi Salem, Kirk N. Campbell, Lewis Kaufman, Paolo Cravedi, Weijia Zhang, Philip J. O'Connell, John Cijiang He, Barbara Murphy and Madhav C. Menon

JASN November 2018, 29 (11) 2641-2657; DOI: https://doi.org/10.1681/ASN.2018060573

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