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Basic ResearchChronic Kidney Disease
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Factor H–Related Protein 1 Drives Disease Susceptibility and Prognosis in C3 Glomerulopathy

Bárbara Márquez-Tirado, Josué Gutiérrez-Tenorio, Agustín Tortajada, Laura Lucientes Continente, Fernando Caravaca-Fontán, Talat H. Malik, Raquel Roldán Montero, Sandra Elías, Ana Saiz Gonzalez, Gema Fernández-Juarez, Pilar Sánchez-Corral, Matthew C. Pickering, Manuel Praga, Santiago Rodríguez de Córdoba and Elena Goicoechea de Jorge
JASN May 2022, ASN.2021101318; DOI: https://doi.org/10.1681/ASN.2021101318
Bárbara Márquez-Tirado
1Department of Immunology, Complutense University and Research Institute Hospital 12 de Octubre (imas12), Madrid, Spain
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Josué Gutiérrez-Tenorio
1Department of Immunology, Complutense University and Research Institute Hospital 12 de Octubre (imas12), Madrid, Spain
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Agustín Tortajada
1Department of Immunology, Complutense University and Research Institute Hospital 12 de Octubre (imas12), Madrid, Spain
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Laura Lucientes Continente
1Department of Immunology, Complutense University and Research Institute Hospital 12 de Octubre (imas12), Madrid, Spain
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Fernando Caravaca-Fontán
2Research Institute Hospital 12 de Octubre (imas12), Madrid, Spain
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Talat H. Malik
3Centre for Inflammatory Disease, Imperial College London, London, United Kingdom
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Raquel Roldán Montero
4Instituto de Investigación Sanitaria–Fundación Jiménez Díaz, Madrid, Spain
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Sandra Elías
5Nephrology Department, Hospital Universitario Ramón y Cajal, Instituto Ramón y Cajal de Investigación Sanitaria (IRYCIS), Madrid, Spain
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Ana Saiz Gonzalez
6Pathological Anatomy, Hospital Universitario Ramón y Cajal, Madrid, Spain
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  • ORCID record for Ana Saiz Gonzalez
Gema Fernández-Juarez
7Nephrology Department, Hospital Universitario Fundación, Alcorcón, Spain
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Pilar Sánchez-Corral
8Hospital La Paz Institute for Health Research (IdiPAZ), La Paz University Hospital, Center for Biomedical Network Research on Rare Diseases (CIBERER), Madrid, Spain
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Matthew C. Pickering
3Centre for Inflammatory Disease, Imperial College London, London, United Kingdom
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Manuel Praga
2Research Institute Hospital 12 de Octubre (imas12), Madrid, Spain
9Department of Medicine, Complutense University of Madrid, Madrid, Spain
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Santiago Rodríguez de Córdoba
10Center for Biological Research and Rare Disease Networking Biomedical Research Center, Madrid, Spain
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Elena Goicoechea de Jorge
1Department of Immunology, Complutense University and Research Institute Hospital 12 de Octubre (imas12), Madrid, Spain
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  • ORCID record for Elena Goicoechea de Jorge
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Journal of the American Society of Nephrology: 33 (5)
Journal of the American Society of Nephrology
Vol. 33, Issue 5
May 2022
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Factor H–Related Protein 1 Drives Disease Susceptibility and Prognosis in C3 Glomerulopathy
Bárbara Márquez-Tirado, Josué Gutiérrez-Tenorio, Agustín Tortajada, Laura Lucientes Continente, Fernando Caravaca-Fontán, Talat H. Malik, Raquel Roldán Montero, Sandra Elías, Ana Saiz Gonzalez, Gema Fernández-Juarez, Pilar Sánchez-Corral, Matthew C. Pickering, Manuel Praga, Santiago Rodríguez de Córdoba, Elena Goicoechea de Jorge
JASN May 2022, ASN.2021101318; DOI: 10.1681/ASN.2021101318

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Factor H–Related Protein 1 Drives Disease Susceptibility and Prognosis in C3 Glomerulopathy
Bárbara Márquez-Tirado, Josué Gutiérrez-Tenorio, Agustín Tortajada, Laura Lucientes Continente, Fernando Caravaca-Fontán, Talat H. Malik, Raquel Roldán Montero, Sandra Elías, Ana Saiz Gonzalez, Gema Fernández-Juarez, Pilar Sánchez-Corral, Matthew C. Pickering, Manuel Praga, Santiago Rodríguez de Córdoba, Elena Goicoechea de Jorge
JASN May 2022, ASN.2021101318; DOI: 10.1681/ASN.2021101318
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Keywords

  • C3 glomerulopathy
  • complement
  • factor H-related protein 1
  • glomerular disease
  • disease susceptibility
  • prognosis
  • genetic renal disease

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