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May 06, 2021

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Increasing mTORC1 Pathway Activity or Methionine Supplementation during Pregnancy Reverses the Negative Effect of Maternal Malnutrition on the Developing Kidney
Yaniv Makayes, Elad Resnick, Liad Hinden, Elina Aizenshtein, Tomer Shlomi, Raphael Kopan, Morris Nechama and Oded Volovelsky

JASN May 2021, ASN.2020091321; DOI: https://doi.org/10.1681/ASN.2020091321

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National Estimates of CKD Prevalence and Potential Impact of Estimating Glomerular Filtration Rate Without Race
Vishal Duggal, I-chun Thomas, Maria E. Montez-Rath, Glenn M. Chertow and Manjula Kurella Tamura

JASN May 2021, ASN.2020121780; DOI: https://doi.org/10.1681/ASN.2020121780

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May 05, 2021

Open Access
Reassessing the Inclusion of Race in Diagnosing Kidney Diseases: An Interim Report from the NKF-ASN Task Force
Cynthia Delgado, Mukta Baweja, Nilka Ríos Burrows, Deidra C. Crews, Nwamaka D. Eneanya, Crystal A. Gadegbeku, Lesley A. Inker, Mallika L. Mendu, W. Greg Miller, Marva M. Moxey-Mims, Glenda V. Roberts, Wendy L. St. Peter, Curtis Warfield and Neil R. Powe

JASN May 2021, ASN.2021010039; DOI: https://doi.org/10.1681/ASN.2021010039

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Open Access
Race and the Estimation of GFR: Getting it Right
Harold I. Feldman and Josephine P. Briggs

JASN May 2021, ASN.2021020206; DOI: https://doi.org/10.1681/ASN.2021020206

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Serine Protease HTRA1 as a Novel Target Antigen in Primary Membranous Nephropathy
Laith Farah Al-Rabadi, Tiffany Caza, Claire Trivin-Avillach, Aylin R. Rodan, Nicole Andeen, Norifumi Hayashi, Brandi Williams, Monica P. Revelo, Fred Clayton, Jo Abraham, Edwin Lin, Willisa Liou, Chang-Jiang Zou, Nirupama Ramkumar, Tim Cummins, Daniel W. Wilkey, Issa Kawalit, Christian Herzog, Aaron Storey, Rick Edmondson, Ronald Sjoberg, Tianxin Yang, Jeremy Chien, Michael Merchant, John Arthur, Jon Klein, Chris Larsen and Laurence H. Beck

JASN May 2021, ASN.2020101395; DOI: https://doi.org/10.1681/ASN.2020101395

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May 03, 2021

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Medical Records-Based Genetic Studies of the Complement System
Atlas Khan, Ning Shang, Lynn Petukhova, Jun Zhang, Yufeng Shen, Scott J. Hebbring, Halima Moncrieffe, Leah C. Kottyan, Bahram Namjou-Khales, Rachel Knevel, Soumya Raychaudhuri, Elizabeth W. Karlson, John B. Harley, Ian B. Stanaway, David Crosslin, Joshua C. Denny, Mitchell S.V. Elkind, Ali G. Gharavi, George Hripcsak, Chunhua Weng and Krzysztof Kiryluk

JASN May 2021, ASN.2020091371; DOI: https://doi.org/10.1681/ASN.2020091371

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Platelet Function in CKD: A Systematic Review and Meta-Analysis
Constance C.F.M.J. Baaten, Marieke Sternkopf, Tobias Henning, Nikolaus Marx, Joachim Jankowski and Heidi Noels

JASN May 2021, ASN.2020101440; DOI: https://doi.org/10.1681/ASN.2020101440

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April 29, 2021

Open Access
SARS-CoV-2 Vaccine Acceptability in Patients on Hemodialysis: A Nationwide Survey
Pablo Garcia, Maria E. Montez-Rath, Heather Moore, Johnie Flotte, Chris Fults, Martha S. Block, Jialin Han, Mary Dittrich, Julie Parsonnet, Glenn M. Chertow, Geoffrey A. Block and Shuchi Anand

JASN April 2021, ASN.2021010104; DOI: https://doi.org/10.1681/ASN.2021010104

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April 28, 2021

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Autonomous Calcium Signaling in Human and Zebrafish Podocytes Controls Kidney Filtration Barrier Morphogenesis
Lydia Djenoune, Ritu Tomar, Aude Dorison, Irene Ghobrial, Heiko Schenk, Jan Hegermann, Lynne Beverly-Staggs, Alejandro Hidalgo-Gonzalez, Melissa H. Little and Iain A. Drummond

JASN April 2021, ASN.2020101525; DOI: https://doi.org/10.1681/ASN.2020101525

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April 23, 2021

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Laminin-521 is a Novel Target of Autoantibodies Associated with Lung Hemorrhage in Anti-GBM Disease
Cong-rong Shen, Xiao-yu Jia, Wentian Luo, Florina Olaru, Zhao Cui, Ming-hui Zhao and Dorin-Bogdan Borza

JASN April 2021, ASN.2020101431; DOI: https://doi.org/10.1681/ASN.2020101431

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Anti Human CX3CR1 VHH Molecule Attenuates Venous Neointimal Hyperplasia of Arteriovenous Fistula in Mouse Model
Sanjay Misra, Sreenivasulu Kilari, Binxia Yang, Amit Sharma, Chih-Cheng Wu, Roberto I. Vazquez-Padron and John Broadwater

JASN April 2021, ASN.2020101458; DOI: https://doi.org/10.1681/ASN.2020101458

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April 22, 2021

Open Access
The Effect of Tolvaptan on BP in Polycystic Kidney Disease: A Post Hoc Analysis of the TEMPO 3:4 Trial
Judith E. Heida, Ron T. Gansevoort, Vicente E. Torres, Olivier Devuyst, Ronald D. Perrone, Jennifer Lee, Hui Li, John Ouyang and Arlene B. Chapman

JASN April 2021, ASN.2020101512; DOI: https://doi.org/10.1681/ASN.2020101512

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April 21, 2021

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Phase 3 Randomized Study Comparing Vadadustat with Darbepoetin Alfa for Anemia in Japanese Patients with Nondialysis-Dependent CKD
Masaomi Nangaku, Kazuoki Kondo, Yoshimasa Kokado, Kiichiro Ueta, Genki Kaneko, Tsubasa Tandai, Yutaka Kawaguchi and Yasuhiro Komatsu

JASN April 2021, ASN.2020091311; DOI: https://doi.org/10.1681/ASN.2020091311

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Exploring the Complexity of Death-Censored Kidney Allograft Failure
Manuel Mayrdorfer, Lutz Liefeldt, Kaiyin Wu, Birgit Rudolph, Qiang Zhang, Frank Friedersdorff, Nils Lachmann, Danilo Schmidt, Bilgin Osmanodja, Marcel G. Naik, Wiebke Duettmann, Fabian Halleck, Marina Merkel, Eva Schrezenmeier, Johannes Waiser, Michael Duerr and Klemens Budde

JASN April 2021, ASN.2020081215; DOI: https://doi.org/10.1681/ASN.2020081215

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April 19, 2021

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3D Mapping Reveals a Complex and Transient Interstitial Matrix During Murine Kidney Development
Sarah N. Lipp, Kathryn R. Jacobson, David S. Hains, Andrew L. Schwarderer and Sarah Calve

JASN April 2021, ASN.2020081204; DOI: https://doi.org/10.1681/ASN.2020081204

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Open Access
Activation of Sympathetic Signaling in Macrophages Blocks Systemic Inflammation and Protects against Renal Ischemia-Reperfusion Injury
Sho Hasegawa, Tsuyoshi Inoue, Yasuna Nakamura, Daichi Fukaya, Rie Uni, Chia-Hsien Wu, Rie Fujii, Wachirasek Peerapanyasut, Akashi Taguchi, Takahide Kohro, Shintaro Yamada, Mikako Katagiri, Toshiyuki Ko, Seitaro Nomura, Atsuko Nakanishi Ozeki, Etsuo A. Susaki, Hiroki R. Ueda, Nobuyoshi Akimitsu, Youichiro Wada, Issei Komuro, Masaomi Nangaku and Reiko Inagi

JASN April 2021, ASN.2020121723; DOI: https://doi.org/10.1681/ASN.2020121723

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April 16, 2021

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A Rare Autosomal Dominant Variant in Regulator of Calcineurin Type 1 (RCAN1) Gene Confers Enhanced Calcineurin Activity and May Cause FSGS
Brandon M. Lane, Susan Murray, Katherine Benson, Agnieszka Bierzynska, Megan Chryst-Stangl, Liming Wang, Guanghong Wu, Gianpiero Cavalleri, Brendan Doyle, Neil Fennelly, Anthony Dorman, Shane Conlon, Virginia Vega-Warner, Damian Fermin, Poornima Vijayan, Mohammad Azfar Qureshi, Shirlee Shril, Moumita Barua, Friedhelm Hildebrandt, Martin Pollak, David Howell, Matthew G. Sampson, Moin Saleem, Peter J. Conlon, Robert Spurney and Rasheed Gbadegesin

JASN April 2021, ASN.2020081234; DOI: https://doi.org/10.1681/ASN.2020081234

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April 15, 2021

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Effects of a Knowledge-Translation Intervention on Early Dialysis Initiation: A Cluster Randomized Trial
Navdeep Tangri, Amit X. Garg, Thomas W. Ferguson, Stephanie Dixon, Claudio Rigatto, Selina Allu, Elaine Chau, Paul Komenda, David Naimark, Gihad E. Nesrallah, Steven D. Soroka, Monica Beaulieu, Ahsan Alam, S. Joseph Kim, Manish M. Sood and Braden Manns

JASN April 2021, ASN.2020091254; DOI: https://doi.org/10.1681/ASN.2020091254

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April 14, 2021

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Pre-emptive Short-term Nicotinamide Mononucleotide Treatment in a Mouse Model of Diabetic Nephropathy
Itaru Yasuda, Kazuhiro Hasegawa, Yusuke Sakamaki, Hirokazu Muraoka, Takahisa Kawaguchi, Ei Kusahana, Takashi Ono, Takeshi Kanda, Hirobumi Tokuyama, Shu Wakino and Hiroshi Itoh

JASN April 2021, ASN.2020081188; DOI: https://doi.org/10.1681/ASN.2020081188

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Could NAD⁺ Precursor Supplements Induce a Legacy of Protection against Diabetic Nephropathy?
Kelly A. Hyndman and Matthew D. Griffin

JASN April 2021, ASN.2021020275; DOI: https://doi.org/10.1681/ASN.2021020275

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Open Access
Diagnosis, Education, and Care of Patients with APOL1-Associated Nephropathy: A Delphi Consensus and Systematic Review
Barry I. Freedman, Wylie Burke, Jasmin Divers, Lucy Eberhard, Crystal A. Gadegbeku, Rasheed Gbadegesin, Michael E. Hall, Tiffany Jones-Smith, Richard Knight, Jeffrey B. Kopp, Csaba P. Kovesdy, Keith C. Norris, Opeyemi A. Olabisi, Glenda V. Roberts, John R. Sedor and Erika Blacksher

JASN April 2021, ASN.2020101399; DOI: https://doi.org/10.1681/ASN.2020101399

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April 13, 2021

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On the Increased Event Rate of Urinary Tract Infection and Pneumonia in CKD Patients Treated with Roxadustat for Anemia
Theodoros Eleftheriadis, Georgios Pissas, Vassilios Liakopoulos and Ioannis Stefanidis

JASN April 2021, ASN.2021020204; DOI: https://doi.org/10.1681/ASN.2021020204

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Authors’ Reply
Steven Fishbane, Mohamed A. El-Shahawy, Bui Pham Van and Dustin J. Little

JASN April 2021, ASN.2021030334; DOI: https://doi.org/10.1681/ASN.2021030334

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April 12, 2021

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Empagliflozin Inhibits Proximal Tubule NHE3 Activity, Preserves GFR, and Restores Euvolemia in Nondiabetic Rats with Induced Heart Failure
Flávio A. Borges-Júnior, Danúbia Silva dos Santos, Acaris Benetti, Juliano Z. Polidoro, Aline C.T. Wisnivesky, Renato O. Crajoinas, Ednei L. Antônio, Leonardo Jensen, Bruno Caramelli, Gerhard Malnic, Paulo J. Tucci and Adriana C.C. Girardi

JASN April 2021, ASN.2020071029; DOI: https://doi.org/10.1681/ASN.2020071029

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April 08, 2021

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Tubuloglomerular Feedback Synchronization in Nephrovascular Networks
Tayyaba Zehra, William A. Cupples and Branko Braam

JASN April 2021, ASN.2020040423; DOI: https://doi.org/10.1681/ASN.2020040423

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Black Race Coefficient in GFR Estimation and Diabetes Medications in CKD: National Estimates
Carl P. Walther, Wolfgang C. Winkelmayer and Sankar D. Navaneethan

JASN April 2021, ASN.2020121724; DOI: https://doi.org/10.1681/ASN.2020121724

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Open Access
Initial Effects of COVID-19 on Patients with ESKD
Eric D. Weinhandl, James B. Wetmore, Yi Peng, Jiannong Liu, David T. Gilbertson and Kirsten L. Johansen

JASN April 2021, ASN.2021010009; DOI: https://doi.org/10.1681/ASN.2021010009

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April 07, 2021

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Advance Care Planning in Older Adults with CKD: Patient, Care Partner, and Clinician Perspectives
Keren Ladin, Isabel Neckermann, Noah D’Arcangelo, Susan Koch-Weser, John B. Wong, Elisa J. Gordon, Ana Rossi, Dena Rifkin, Tamara Isakova and Daniel E. Weiner

JASN April 2021, ASN.2020091298; DOI: https://doi.org/10.1681/ASN.2020091298

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April 02, 2021

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Defects in KCNJ16 Cause a Novel Tubulopathy with Hypokalemia, Salt Wasting, Disturbed Acid-Base Homeostasis, and Sensorineural Deafness
Karl P. Schlingmann, Aparna Renigunta, Ewout J. Hoorn, Anna-Lena Forst, Vijay Renigunta, Velko Atanasov, Sinthura Mahendran, Tahsin Stefan Barakat, Valentine Gillion, Nathalie Godefroid, Alice S. Brooks, Dorien Lugtenberg, Jennifer Lake, Huguette Debaix, Christoph Rudin, Bertrand Knebelmann, Stephanie Tellier, Caroline Rousset-Rouvière, Daan Viering, Jeroen H. F. deBaaij, Stefanie Weber, Oleg Palygin, Alexander Staruschenko, Robert Kleta, Pascal Houillier, Detlef Bockenhauer, Olivier Devuyst, Rosa Vargas-Poussou, Richard Warth, Anselm A. Zdebik and Martin Konrad

JASN April 2021, ASN.2020111587; DOI: https://doi.org/10.1681/ASN.2020111587

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April 01, 2021

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Medicaid Expansion and Incidence of Kidney Failure among Nonelderly Adults
Rebecca Thorsness, Shailender Swaminathan, Yoojin Lee, Benjamin D. Sommers, Rajnish Mehrotra, Kevin H. Nguyen, Daeho Kim, Maricruz Rivera-Hernandez and Amal N. Trivedi

JASN April 2021, ASN.2020101511; DOI: https://doi.org/10.1681/ASN.2020101511

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The Basolateral Polarity Module Promotes Slit Diaphragm Formation in Drosophila Nephrocytes, a Model of Vertebrate Podocytes
Michael Mysh and John S. Poulton

JASN April 2021, ASN.2020071050; DOI: https://doi.org/10.1681/ASN.2020071050

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March 30, 2021

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ADAM10-Mediated Ectodomain Shedding Is an Essential Driver of Podocyte Damage
Marlies Sachs, Sebastian Wetzel, Julia Reichelt, Wiebke Sachs, Lisa Schebsdat, Stephanie Zielinski, Lisa Seipold, Lukas Heintz, Stephan A. Müller, Oliver Kretz, Maja Lindenmeyer, Thorsten Wiech, Tobias B. Huber, Renate Lüllmann-Rauch, Stefan F. Lichtenthaler, Paul Saftig and Catherine Meyer-Schwesinger

JASN March 2021, ASN.2020081213; DOI: https://doi.org/10.1681/ASN.2020081213

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Causal Effects of Positive Affect, Life Satisfaction, Depressive Symptoms, and Neuroticism on Kidney Function: A Mendelian Randomization Study
Sehoon Park, Soojin Lee, Yaerim Kim, Yeonhee Lee, Min Woo Kang, Kwangsoo Kim, Yong Chul Kim, Seung Seok Han, Hajeong Lee, Jung Pyo Lee, Kwon Wook Joo, Chun Soo Lim, Yon Su Kim and Dong Ki Kim

JASN March 2021, ASN.2020071086; DOI: https://doi.org/10.1681/ASN.2020071086

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March 26, 2021

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Super-Enhancer-Associated Transcription Factors Maintain Transcriptional Regulation in Mature Podocytes
Jingping Yang, Difei Zhang, Masaru Motojima, Tsutomu Kume, Qing Hou, Yu Pan, Aiping Duan, Mingchao Zhang, Song Jiang, Jinhua Hou, Jingsong Shi, Zhaohui Qin and Zhihong Liu

JASN March 2021, ASN.2020081177; DOI: https://doi.org/10.1681/ASN.2020081177

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March 25, 2021

Open Access
A Randomized Trial of Tenapanor and Phosphate Binders as a Dual-Mechanism Treatment for Hyperphosphatemia in Patients on Maintenance Dialysis (AMPLIFY)
Pablo E. Pergola, David P. Rosenbaum, Yang Yang and Glenn M. Chertow

JASN March 2021, ASN.2020101398; DOI: https://doi.org/10.1681/ASN.2020101398

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Low Health Literacy is Associated with the Onset of CKD during the Life Course
Matheus S. Gurgel do Amaral, Sijmen A. Reijneveld, Bas Geboers, Gerjan J. Navis and Andrea F de Winter

JASN March 2021, ASN.2020081155; DOI: https://doi.org/10.1681/ASN.2020081155

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March 23, 2021

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Hypercholesterolemia in Progressive Renal Failure Is Associated with Changes in Hepatic Heparan Sulfate - PCSK9 Interaction
Pragyi Shrestha, Saritha Adepu, Romain R. Vivès, Rana El Masri, Astrid Klooster, Fleur Kaptein, Wendy Dam, Stephan J. L. Bakker, Harry van Goor, Bart van de Sluis and Jacob van den Born

JASN March 2021, ASN.2020091376; DOI: https://doi.org/10.1681/ASN.2020091376

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March 22, 2021

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Safety and Efficacy of Vitamin K Antagonists versus Rivaroxaban in Hemodialysis Patients with Atrial Fibrillation: A Multicenter Randomized Controlled Trial
An S. De Vriese, Rogier Caluwé, Hans Van Der Meersch, Koen De Boeck and Dirk De Bacquer

JASN March 2021, ASN.2020111566; DOI: https://doi.org/10.1681/ASN.2020111566

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March 16, 2021

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Dysregulation of Principal Cell miRNAs Facilitates Epigenetic Regulation of AQP2 and Results in Nephrogenic Diabetes Insipidus
Federica Petrillo, Anna Iervolino, Tiziana Angrisano, Sabina Jelen, Vincenzo Costanzo, Mariavittoria D’Acierno, Lei Cheng, Qi Wu, Ilaria Guerriero, Maria Cristina Mazzarella, Alfonso De Falco, Fulvio D’Angelo, Michele Ceccarelli, Michele Caraglia, Giovambattista Capasso, Robert A. Fenton and Francesco Trepiccione

JASN March 2021, ASN.2020010031; DOI: https://doi.org/10.1681/ASN.2020010031

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March 15, 2021

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How to Get Started with Single Cell RNA Sequencing Data Analysis
Michael S. Balzer, Ziyuan Ma, Jianfu Zhou, Amin Abedini and Katalin Susztak

JASN March 2021, ASN.2020121742; DOI: https://doi.org/10.1681/ASN.2020121742

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