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Basic Research
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Data-driven Derivation and Validation of Novel Phenotypes for Acute Kidney Transplant Rejection using Semi-supervised Clustering

Thibaut Vaulet, Gillian Divard, Olivier Thaunat, Evelyne Lerut, Aleksandar Senev, Olivier Aubert, Elisabet Van Loon, Jasper Callemeyn, Marie-Paule Emonds, Amaryllis Van Craenenbroeck, Katrien De Vusser, Ben Sprangers, Maud Rabeyrin, Valérie Dubois, Dirk Kuypers, Maarten De Vos, Alexandre Loupy, Bart De Moor and Maarten Naesens
JASN March 2021, ASN.2020101418; DOI: https://doi.org/10.1681/ASN.2020101418
Thibaut Vaulet
1Department of Electrical Engineering, Stadius Center for Dynamical Systems, Signal Processing and Data Analytics, KU Leuven, Leuven, Belgium
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Gillian Divard
2Université de Paris, National Institutes of Health and Medical Research, Paris Translational Research Centre for Organ Transplantation, Paris, France
3Kidney Transplant Department, Necker Hospital, Assistance Publique Hôpitaux de Paris, Paris, France
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Olivier Thaunat
4French National Institutes of Health and Medical Research, Lyon, France
5Department of Transplantation, Nephrology and Clinical Immunology, Hospices Civils de Lyon, Edouard Herriot Hospital, Lyon, France
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Evelyne Lerut
6Department of Imaging and Pathology, University Hospitals Leuven, Leuven, Belgium
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Aleksandar Senev
7Department of Microbiology, Immunology and Transplantation, KU Leuven, Leuven, Belgium
8Histocompatibility and Immunogenetics Laboratory, Belgian Red Cross—Flanders, Mechelen, Belgium
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  • ORCID record for Aleksandar Senev
Olivier Aubert
2Université de Paris, National Institutes of Health and Medical Research, Paris Translational Research Centre for Organ Transplantation, Paris, France
3Kidney Transplant Department, Necker Hospital, Assistance Publique Hôpitaux de Paris, Paris, France
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Elisabet Van Loon
7Department of Microbiology, Immunology and Transplantation, KU Leuven, Leuven, Belgium
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  • ORCID record for Elisabet Van Loon
Jasper Callemeyn
7Department of Microbiology, Immunology and Transplantation, KU Leuven, Leuven, Belgium
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  • ORCID record for Jasper Callemeyn
Marie-Paule Emonds
7Department of Microbiology, Immunology and Transplantation, KU Leuven, Leuven, Belgium
8Histocompatibility and Immunogenetics Laboratory, Belgian Red Cross—Flanders, Mechelen, Belgium
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Amaryllis Van Craenenbroeck
7Department of Microbiology, Immunology and Transplantation, KU Leuven, Leuven, Belgium
9Department of Nephrology and Kidney Transplantation, University Hospitals Leuven, Leuven, Belgium
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Katrien De Vusser
7Department of Microbiology, Immunology and Transplantation, KU Leuven, Leuven, Belgium
9Department of Nephrology and Kidney Transplantation, University Hospitals Leuven, Leuven, Belgium
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Ben Sprangers
7Department of Microbiology, Immunology and Transplantation, KU Leuven, Leuven, Belgium
9Department of Nephrology and Kidney Transplantation, University Hospitals Leuven, Leuven, Belgium
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Maud Rabeyrin
10Department of Pathology, Hospices Civils de Lyon, Bron, France
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Valérie Dubois
11French National Blood Service, Décines-Charpieu, France
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Dirk Kuypers
7Department of Microbiology, Immunology and Transplantation, KU Leuven, Leuven, Belgium
9Department of Nephrology and Kidney Transplantation, University Hospitals Leuven, Leuven, Belgium
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Maarten De Vos
1Department of Electrical Engineering, Stadius Center for Dynamical Systems, Signal Processing and Data Analytics, KU Leuven, Leuven, Belgium
12Department of Development and Regeneration, University Hospitals Leuven, KU Leuven, Leuven, Belgium
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Alexandre Loupy
2Université de Paris, National Institutes of Health and Medical Research, Paris Translational Research Centre for Organ Transplantation, Paris, France
3Kidney Transplant Department, Necker Hospital, Assistance Publique Hôpitaux de Paris, Paris, France
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Bart De Moor
1Department of Electrical Engineering, Stadius Center for Dynamical Systems, Signal Processing and Data Analytics, KU Leuven, Leuven, Belgium
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Maarten Naesens
7Department of Microbiology, Immunology and Transplantation, KU Leuven, Leuven, Belgium
9Department of Nephrology and Kidney Transplantation, University Hospitals Leuven, Leuven, Belgium
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