PT  - JOURNAL ARTICLE
AU  - Alejandro, D S
AU  - Petersen, J
TI  - Myoglobinuric acute renal failure in a cardiac transplant patient taking lovastatin and cyclosporine.
AID  - 10.1681/ASN.V52153
DP  - 1994 Aug 01
TA  - Journal of the American Society of Nephrology
PG  - 153--160
VI  - 5
IP  - 2
4099  - http://jasn.asnjournals.org/content/5/2/153.short
4100  - http://jasn.asnjournals.org/content/5/2/153.full
SO  - J. Am. Soc. Nephrol.1994 Aug 01; 5
AB  - Acute renal failure can occur in cardiac transplant patients for a variety of reasons. A case of a patient who developed acute renal failure secondarily to drug-induced rhabdomyolysis is reported. The literature regarding acute renal failure and lovastatin and other 3-hydroxy-3-methylglutaryl-coenzyme A reductase inhibitors is reviewed. The potential mechanisms of myoglobinuria and nephrotoxicity and the therapeutic implications are discussed.