Table 4.

Renal biopsy findings in 16 patients with PAPSa

Patient Glomeruli Interstitium Vessels Involved FCA
Interlobular Arteries Arteriolar Lesions
n Global Sclerosis Lesions Fibrosis Tubular Atrophy Thyroidization Arteriosclerosis Fibrointimal Hyperplasia Organizing Thrombosis Hyalinosis Sclerosis TMA Occlusions
1204Double contour10%+-++++++-+++-
24012 (FCA)10%++-++++-+-++
312040%++++--+--+
4305TMA, FSGS40%+--+++++++++++-
5200TMA, FSGS20%+-+++-++++--
6109 (FCA)75%++++-+--+-++
7126 (FCA)10%++-+--+-++
874Double contour70%+++++++-++++
915530%+++--++---
1010210FSGS (FCA)10%+++---+-++
112010 (FCA)30%+++++-+-++
12131Collapsed glom.10%+++--++---
1312110%+++---+---
142212 (FCA)Collapsed glom.40%++++++++-++-++
1510050%+-++--+-++
16 20 10 (FCA) Double contour 10% + + + + - + - + - +
  • a FCA, focal cortical atrophy; TMA, thrombotic microangiopathy with fibrin occlusion; FSGS, focal segmental glomerulosclerosis, +, focal lesions; ++, diffuse lesions.