Table 3.

Mineral metabolism in male patients with different stages of renal failurea

ParameterControl (n = 9)RP1b (n = 6)RP2c (n = 13)RP3d (n = 8)
aReprinted with permission from Kidney International (57). Results are given as mean ± SD.
bRP1 = GFR >70 ml/min.
cRP2 = GFR between 30 and 70 ml/min.
dRP3 = GFR <30 ml/min.
eP < 0.05 versus C.
fP < 0.05 versus RP1.
gP < 0.05 versus RP2.
Age (yr)40.3 ± 11.139.5 ± 19.241.0 ± 12.147.0 ± 13.6
Creatinine clearance (ml/min)125.1 ± 23110.3 ± 2963.1 ± 18.5e,f25.6 ± 13e,f,g
Ionized calcium (mM)1.27 ± 0.031.26 ± 0.041.27 ± 0.061.26 ± 0.03
Phosphorus (mM)1.11 ± 0.100.98 ± 0.230.98 ± 0.241.10 ± 0.25
Intact PTH (pg/ml)26.2 ± 12.722.0 ± 5.239.0 ± 13.2e142.1 ± 79.4e,f,g
Calcitriol (pg/ml)39.9 ± 9.735.2 ± 7.227.2 ± 12.0e,f14.0 ± 7.3e,f,g
25-OHD (ng/ml)23.6 ± 9.321.3 ± 6.124.9 ± 10.519.3 ± 11.7
Maximal PTH (pg/ml)87.4 ± 28.880.2 ± 18138 ± 25.7e,f312 ± 29.3e,f,g
Minimal PTH (pg/ml)8.5 ± 3.412.5 ± 7.816.2 ± 12.229.3 ± 15.3e,g
Basal/maximal PTH (%)27 ± 1228 ± 729 ± 946 ± 17e,f,g