Table 2.

Comparison of the mass removal rate by ultrafiltration (MUF) and by adsorption (MAD) for the two blood flow rates (QB)a

CytokineTimebMUF (pg/min) QB = 100 ml/minMUF (pg/min)cQB = 200 ml/minMAD (pg/min) QB = 100 ml/minMAD (pg/min) QB = 200 ml/min
aTNF-α, tumor necrosis factor-α; IL-1β, interleukin-1β; sTNFR-I and sTNFR-II, soluble tumor necrosis factor receptor I and II, respectively; IL-1ra, interleukin-1 receptor antagonist.
bThe results for the corresponding time points after use of a new hemofilter (t = 1/13, t = 6/18, and t = 12/24) are pooled.
cBoth MUF and MAD are significantly higher at a QB of 200 ml/min versus a QB of 100 ml/min (* P < 0.05). No statistical analysis was performed for IL-1β, since it was detected in only five patients.
TNF-αt = 1/13145.7 ± 16.0221.9 ± 44.6*1343.3 ± 388.22076.5 ± 497.0*
t = 6/18159.8 ± 23.7284.5 ± 62.4*749.6 ± 171.01524.9 ± 310.6*
t = 12/24138.3 ± 21.8315.0 ± 54.2*983.3 ± 242.91000.5 ± 303.4
IL-1βt = 1/1391.3 ± 58.2131.1 ± 86.3331.6 ± 67.6417.7 ± 123.7
t = 6/1889.0 ± 65.8151.0 ± 100.3226.5 ± 78.4390.6 ± 143.1
t = 12/2499.3 ± 69.7106.4 ± 106.4192.5 ± 40.0329.8 ± 157.0
IL-6t = 1/1313579 ± 602931887 ± 20941*83421 ± 55676132355 ± 73592*
t = 6/1821388 ± 1029438409 ± 20735*30800 ± 1342968688 ± 31518*
t = 12/2419833 ± 1159826668 ± 18383*48636 ± 4472291712 ± 47601*
sTNFR-It = 1/131928 ± 5653242 ± 1067*319835 ± 43965514455 ± 74705*
t = 6/183615 ± 12425981 ± 2271*323228 ± 50420452200 ± 64352*
t = 12/244185 ± 12055205 ± 2232170715 ± 44947379496 ± 93805*
sTNFR-IIt = 1/131865 ± 483163 ± 135*602245 ± 79116900674 ± 109945*
t = 6/182042 ± 823454 ± 161*468669 ± 77832671553 ± 45149*
t = 12/241800 ± 653295 ± 121*190996 ± 74328485838 ± 89494*
IL-1rat = 1/1351782 ± 20873100356 ± 41529*266462 ± 69479402523 ± 112750*
t = 6/1865531 ± 16943139372 ± 45081*193912 ± 68635278982 ± 79789*
t = 12/2464605 ± 1718187370 ± 23687159072 ± 45199296765 ± 123296*
IL-10t = 1/130 ± 00 ± 010523 ± 251017164 ± 4371*
t = 6/180 ± 00 ± 08660 ± 246414028 ± 3625*
t = 12/240 ± 00 ± 06632 ± 17299612 ± 3218