Table 4.

Clinical characteristics of 55 normotensive patients with type 1 diabetes by C708/T polymorphism and ScaI at the atrial natriuretic peptide genea

CharacteristicC708/C (n = 31)C708/T (n = 24)P ValuebA2/A2 (n = 33)A2/A1 (n = 22)P Valueb
aAbbreviations as in Table 1.
bTwo-tailed t test.
Gender (M/F)14/1711/13NS15/1810/12NS
Age (yr)36 ± 737 ± 9NS36 ± 839 ± 8NS
Diabetes duration (yr)18 ± 719 ± 8NS18 ± 720 ± 8NS
BMI (kg/m2)23.5 ± 1.822.6 ± 1.7NS23.4 ± 1.723.0 ± 1.7NS
SBP (mmHg)124 ± 9119 ± 15NS121 ± 18124 ± 8NS
DBP (mmHg)77 ± 677 ± 6NS77 ± 678 ± 6NS
Serum creatinine (mg/dl)0.87 (0.84 to 0.90)0.91 (0.86 to 0.97)NS0.86 (0.84 to 0.91)0.90 (0.86 to 0.96)NS
HbA1c (%)8.3 ± 1.08.2 ± 1.1NS8.3 ± 1.08.1 ± 1.4NS
HbA1c (%), mean of previous 2 yr8.3 ± 1.38.3 ± 1.4NS8.4 ± 1.38.2 ± 1.4NS
Fasting plasma glucose (mg/dl)206 ± 80212 ± 76NS209 ± 80203 ± 60NS
Plasma volume (ml)2674 ± 3332539 ± 519NS2719 ± 4492452 ± 363NS
Urinary sodium excretion (mmol/24 h)120 ± 10122 ± 13NS122 ± 9121 ± 12NS