Table 3.

Effect of AGE-BSA on PKC isoform translocation to the plasma membrane in cultured human mesangial cellsa

GroupBSA ControlAGE-BSAAGE-BSA + AMGD
aData are actin-normalized densitometry ratios from one experiment representative of n = 3, 60-min treatment of independent monolayers with 2 mg/ml BSA protein. PKC, protein kinase C.
PKC α
cytosol0.490.670.67
membrane0.200.190.08
PKC ζ
cytosol0.830.570.74
membrane0.780.560.39
PKC δ
cytosol1.522.392.41
membrane000