Table 3.

Adjusted odds ratios for pre-ESRD hypoalbuminemia, hematocrit <28%, and EPO use in different geographic regions of the United Statesa

ESRD NetworkbHypoalbuminemiac (n = 67,841)Hematocrit <28% (n = 117,835)EPO Use (n = 117,835)
aAdjusted for age, gender, race, insurance, employment status, diabetes, inability to transfer, inability to ambulate, initial dialysis modality, and year. The ESRD network closest to the national average for prevalence of hypoalbuminemia, hematocrit <28%, and EPO use was used as the reference group for the respective multivariate models.
bESRD Network 1: CT, MA, ME, NH, RI, VT; ESRD Network 2: NY; ESRD Network 3: NJ, PR, VI; ESRD Network 4: DE, PA; ESRD Network 5: DC, MD, VA, WV; ESRD Network 6: GA, NC, SC; ESRD Network 7: FL; ESRD Network 8: AL, MS, TN; ESRD Network 9: IN, KY, OH; ESRD Network 10: IL; ESRD Network 11: MI, MN, ND, SD, WI; ESRD Network 12: IA, KS, MO, NE; ESRD Network 13: AR, LA, OK; ESRD Network 14: TX; ESRD Network 15: AZ, CO, NM, NV, UT, WY; ESRD Network 16: AK, ID, MT, OR, WA; ESRD Network 17: AS, CA (northern), HI, GU; ESRD Network 18: CA (southern).
cHypoalbuminemia was defined as serum albumin below the lower limit of normal recorded in the HCFA 2728 Form in each patient.
10.99 (0.87 to 1.13)0.84 (0.78 to 0.91)1.40 (1.28 to 1.54)
20.88 (0.79 to 0.98)0.99 (0.93 to 1.06)1.22 (1.13 to 1.33)
31.20 (1.08 to 1.34)0.95 (0.88 to 1.01)1.00 (1.00 to 1.00)
41.22 (1.09 to 1.36)0.90 (0.85 to 0.96)0.95 (0.87 to 1.03)
51.08 (0.96 to 1.21)0.93 (0.87 to 0.99)1.04 (0.96 to 1.13)
60.95 (0.86 to 1.05)0.96 (0.91 to 1.02)0.75 (0.69 to 0.81)
70.95 (0.85 to 1.06)0.86 (0.80 to 0.91)1.17 (1.08 to 1.27)
81.02 (0.90 to 1.15)1.06 (0.99 to 1.14)0.92 (0.84 to 1.00)
91.14 (1.03 to 1.27)1.00 (1.00 to 1.00)0.90 (0.83 to 0.97)
101.26 (1.13 to 1.41)0.95 (0.89 to 1.02)0.64 (0.58 to 0.70)
111.00 (0.90 to 1.12)0.97 (0.92 to 1.03)0.89 (0.82 to 0.96)
121.14 (1.01 to 1.28)0.95 (0.88 to 1.02)1.22 (1.12 to 1.34)
131.35 (1.20 to 1.52)0.90 (0.84 to 0.97)0.79 (0.72 to 0.86)
141.00 (0.90 to 1.11)1.03 (0.97 to 1.10)1.19 (1.10 to 1.29)
150.98 (0.87 to 1.10)0.83 (0.77 to 0.89)0.77 (0.70 to 0.84)
160.98 (0.86 to 1.11)0.64 (0.59 to 0.69)1.27 (1.16 to 1.40)
171.00 (1.00 to 1.00)0.84 (0.78 to 0.90)1.51 (1.39 to 1.65)
181.03 (0.93 to 1.14)0.83 (0.78 to 0.88)1.18 (1.09 to 1.27)