Table 1.

Parameters of type II diabetes in the db/db micea

Parameter1 mo (n = 21 to 35)2 mo (n = 21 to 35)3 mo (n = 21 to 35)4 mo (n = 8)
Leandb/dbLeandb/dbLeandb/dbLeandb/db
aUalb/Ucreat, ratio of urine albumin excretion to urine creatinine excretion.
bP < 0.001.
cP < 0.005.
Body weight (g)23.2 ± 1.238.2 ± 0.9b21.8 ± 0.847.1 ± 0.9b23.0 ± 0.749.9 ± 1.2b25.6 ± 0.537.1 ± 2.2b
Plasma glucose (mM)11.1 ± 0.230.0 ± 1.5b11.4 ± 0.338.9 ± 0.8b11.7 ± 0.240.9 ± 1.5b12.2 ± 0.945.4 ± 1.1b
Ualb/Ucreat (μg/μg)0.075 ± 0.031.470 ± 0.37c0.070 ± 0.031.530 ± 0.44c0.069 ± 0.010.910 ± 0.29c0.054 ± 0.022.398 ± 0.35c