Table 2.

Characteristics of cadaveric renal transplant recipients from January 1987 to September 1998 (n = 522) grouped as number suitable for analysis in each intervala

VariableInterval 1 ≤6 mo (n = 522, 100%)Interval 2 6 mo to 5 yr (n = 463, 88.7%)Interval 3 >5 yr (n = 187, 35.8%)
aCMV, cytomegalovirus; PRA, panel-reactive antibodies; SCr, serum creatinine; DGF, delayed graft function.
bIn interval 1, we included only the rejections occurring before 6 mo. Otherwise, we included all rejections requiring antibody therapy. There were no rejections requiring antibody therapy in the third interval.
Donor age (mean ± SD)34.1 ± 15.633.9 ± 15.533.5 ± 14.4
% donor age ≥55 yr9.68.56.5
% donor female40.440.134.8
% donor CMV+49.749.552.9
Recipient age (mean ± SD)42.9 ± 14.142.9 ± 14.142.1 ± 13.3
% recipient age ≥55 yr21.621.619.8
% recipient female36.436.339.0
% recipient CMV+70.669.969.0
% retransplant21.320.518.2
% disease recurrent7.37.69.1
% with PRA high ≥50%15.213.615.8
% with PRA recent ≥50%6.56.46.5
HLA-A,B mismatch (mean ± SD)2.8 ± 1.02.8 ± 1.02.8 ± 1.0
HLA-DR mismatch (mean ± SD)1.2 ± 0.71.2 ± 0.71.1 ± 0.6
% HLA-A,B mismatch >262.862.062.4
% HLA-DR mismatch >133.631.729.2
% SCr at 6 mo ≥150 μmol/LNA36.632.3
% DGF32.229.830.5
% rejection AB19.219.4a18.7b