Table 2.

Comparison of clinical parameters and urinary excretion of CAP before and after sodium bicarbonate administrationa

Treatment by Sodium BicarbonateSCr (mg/dl)UP/UCrHCO3- (mEq/L)BE (mEq/L)P-iC3b (μg/ml)P-Bb (μg/ml)P-MAC (ng/ml)U-iC3b/UCrU-Bb/UCrU-MAC/UCr
aCAP, complement activation products; BE, base excess; P, plasma; MAC, membrane attack complex. Other abbreviations as in Table 1.
bP < 0.01 before versus after (by Wilcoxon test).
cP < 0.05 before versus after (by Wilcoxon test).
Before (n = 11)4.32 ± 0.412.32 ± 0.4016.4 ± 0.66-8.51 ± 0.6327.50 ± 7.360.55 ± 0.07172.59 ± 38.7122.80 ± 9.501.05 ± 0.31315.34 ± 98.04
After (n = 11)4.39 ± 0.481.96 ± 0.3821.33 ± 0.66b-2.44 ± 0.64b24.90 ± 6.520.56 ± 0.09186.23 ± 44.9312.95 ± 4.31c0.78 ± 0.26c199.82 ± 73.34b