Table 3.

Histomorphometric parameters of bone in 57 patients after renal transplantationa

ParameterMean ± SEMRangeNormal Values% of Patients with Values:
LowNormalHigh
aNA, not applicable.
bOsteoid thickness values are corrected for obliquity, i.e., divided by 1.199.
cMaximum osteoid seam thickness is measured directly, i.e., uncorrected.
Bone volume/tissue volume (%)18.6 ± 0.846.77 to 34.116.8 to 22.956.128.115.8
Activation frequency (yr-1)0.62 ± 0.120.01 to 4.550.29 to 0.7245.628.126.3
Osteoblast number/bone length (n/100 mm)218 ± 32.02 to 96410 to 24010.561.428.1
Erosion surface/bone surface (%)3.43 ± 0.530.1 to 18.50.1 to 5.6919.359.621.1
Osteoclast number/bone length (n/100 mm)24.0 ± 3.580.10 to 97.10.01 to 36.128.149.122.8
Bone formation rate/tissue volume (mm3/cm3 per yr)21.6 ± 5.760.12 to 14011.5 to 11059.735.05.3
Fibrosis surface/bone surface (%)0.37 ± 0.150 to 5.760NA84.215.8
Woven osteoid surface/bone surface (%)1.67 ± 0.540 to 22.50NA57.942.1
Osteoid volume/tissue volume (%)8.1 ± 0.870.68 to 32.70.57 to 6.0045.654.4
Osteoid surface/bone surface (%)40.1 ± 2.775.87 to 84.13.45 to 37.9050.949.1
Mean osteoid thickness (μm)b8.94 ± 0.344.53 to 14.74.38 to 11.8084.215.8
Maximum osteoid thickness (μm)c18.0 ± 1.039.6 to 33.2<20NA63.936.1
Mineralization lag time (days)280 ± 43.438.8 to 1,61313.3 to 58.4012.587.5
Osteoid maturation time (days)24.7 ± 1.809.77 to 50.07.1 to 24.6073.726.3
Off time (%)279 ± 43.437.8 to 1,6122 to 46501.898.2