Table 1.

Effect of antiviral drugs in HCV-positive renal transplant patients a

Drug and StudyNo. of PatientsDecrease in Serum ALT (%)Virologic Response (%)Improvement in Liver Histology (%)Acute Renal Failure (%)Interferon-α DoseRibavirin Dose
aHCV, hepatitis C virus ; ALT, alanine aminotransferase ; NA, not available ; MU, million units.
bThree times a week.
cTwo times a week.
Interferon
Rao et al. (47)580NA8003 MU b
Harihara et al. (48)36633NA1003 to 6 MU c
Thervet et al. (49)137.7NANA153 or 5 MU b
Rostaing et al. (50)1677257537.53 MU b
Magnone et al. (51)11NANANA641.5 or 5 MU b
Ozgür et al. (52)560NANA404.5 MU b
Hanafusa et al. (53)108030NA409 MU b
Ribavirin
Garnier et al. (54)75728.5NA0400 to 800 mg/d for 6 mo