Table 2.

Main drugs responsible for rhabdomyolysis, together with the mechanism causing ARFa

AgentCompressionMyotoxicityHypokalemiaOther
aARF, acute renal failure; CNS, central nervous system.
Alcohol+++Hypophosphatemia
AmphetamineAgitation
Amphotericin B+
Antimalarials+
Carbon monoxide+Energy deficiency, hypoxia
CNS depressants+
CocaineHyperthermia, agitation
Colchicine+
Corticosteroids+
Diuretics+
EcstasyAgitation
Fibrates+
HMG-CoA reductase inhibitors+
Heroin++
Isoniazid+
Laxatives+
Licorice+
Narcotics+
Phencyclidine (PCP)+Agitation, seizures
Zidovudine+