Table 4.

Comparison of 21 type 2 biopsies that have been classified as having either diffuse or nodular glomerulosclerosisa

VariableDiffuse (n = 8)Nodular (n = 13)P Value
aData are expressed as mean ± SD or *median (range). Patients with nodules have greater mesangial and matrix volume fractions and more proteinuria than those with diffuse glomerulosclerosis. Creatinine clearance did not differ significantly between the groups. TP, total proteinuria; CC, creatinine clearance.
VvMes/Glom0.36 ± 0.080.51 ± 0.120.007
VvMat/Glom0.21 ± 0.050.32 ± 0.080.003
TP g/24 h*1.1 (0.9 to 12.7)4.3 (1.1 to 9.6)0.027
CC ml/min83 ± 4153 ± 260.053