Table 2.

AGE immunolocalization in diabetic nephropathy versus nondiabetic renal diseasesa

AGE Immunolocalization (%)b
Sclerotic GlomeruliGBMMesangiumTBMInterstitiumVessels
CMLPENTCMLPENTCMLPENTCMLPENTCMLPENTCMLPENT
aAGE, advanced glycation end products; FSGS, focal segmental glomerulosclerosis.
bExpressed as percentage of cases with any positive immunostaining.
cExpressed as percentage of cases with 2+ or 3+ immunostaining.
Diabetic nephropathy94.487.842.33.996.276.984.630.815.492.396.253.9
Primary FSGS71.4100.050.010.020.040.030.050.010.070.040.030.0
Secondary FSGS40.060.00.00.014.385.714.30.014.328.628.614.3
Hypertensive nephrosclerosis100.071.442.90.028.628.685.728.642.957.1100.085.7
Lupus nephritis80.060.054.545.527.363.627.336.40.090.954.518.2
AGE Immunolocalization (%)c
Sclerotic GlomeruliGBMMesangiumTBMInterstitiumVessels
CMLPENTCMLPENTCMLPENTCMLPENTCMLPENTCMLPENT
Diabetic nephropathy77.855.618.23.930.830.853.811.53.961.580.819.2
Primary FSGS14.3100.00.00.00.00.010.030.010.030.030.010.0
Secondary FSGS20.040.00.00.00.00.00.00.00.00.00.00.0
Hypertensive nephrosclerosis57.171.40.00.00.00.028.628.60.028.6100.028.6
Lupus nephritis60.040.09.127.39.118.20.018.20.027.318.29.1