Table 1.

Micropuncture data at 4 to 6 wk after 5/6 nephrectomya

Parameter Body Weight (g) Hct (%) MAP (mmHg) RPF (ml/min) GFR (ml/min) FF CA (g/dl) PGC (mmHg) PT (mmHg) PE (mmHg) ΔP (mmHg) SNGFR (nl/min) QA (nl/min) RA × 1010 (dyne · s · cm-5) RE × 1010 (dyne · s · cm-5) Kf [nl/(s · mmHg)]
aHct, hematocrit; MAP, mean arterial pressure; RPF, renal plasma flow; FF, filtration fraction; CA, afferent arteriolar protein concentration; PGC, glomerular capillary hydraulic pressure; PT, proximal tubule hydraulic pressure; PE, efferent arteriolar hydraulic pressure; ΔP, glomerular transcapillary hydraulic pressure difference; SNGFR, single-nephron GFR; QA, glomerular plasma flow rate; RA, afferent arteriolar resistance; RE, efferent arteriolar resistance; Kf, glomerular capillary ultrafiltration coefficient.
bP < 0.05 versus control value.
cP < 0.05 for combined 25 and 150 mg/L ENA data or combined 25 and 150 mg/L OMA data versus control value.
dP < 0.05 for combined 25 and 150 mg/L OMA data versus combined 25 and 150 mg/L ENA data.
Control 279 ± 7 45 ± 1 143 ± 5 1.4 ± 0.2 0.44 ± 0.05 0.33 ± 0.03 4.8 ± 0.1 62 ± 3 14 ± 1 25 ± 2 48 ± 4 76 ± 8 237 ± 26 1.62 ± 0.20 1.20 ± 0.15 0.048 ± 0.006
ENA (25 mg/L) 300 ± 7 40 ± 1b 97 ± 6b 2.7 ± 0.4b 0.62 ± 0.06 0.26 ± 0.02b 4.6 ± 0.1 53 ± 3 12 ± 1 19 ± 1 41 ± 2 84 ± 6 334 ± 23 0.63 ± 0.06b 0.73 ± 0.09 0.065 ± 0.009
OMA (25 mg/L) 306 ± 6 40 ± 1 93 ± 3b 2.7 ± 0.3b 0.61 ± 0.07 0.22 ± 0.00b 4.7 ± 0.1 47 ± 3b 11 ± 1 18 ± 1b 36 ± 3b 61 ± 7 275 ± 28 0.84 ± 0.10b 0.79 ± 0.12 0.063 ± 0.011
ENA (150 mg/L) 284 ± 7 40 ± 1b,c 85 ± 2b,c 2.6 ± 0.3c 0.54 ± 0.07 0.21 ± 0.01b,c 4.6 ± 0.1 49 ± 2b,c 11 ± 1 20 ± 1c 38 ± 2c 56 ± 6 275 ± 30 0.69 ± 0.11b,c 0.82 ± 0.11c 0.047 ± 0.006
OMA (150 mg/L) 283 ± 5 40 ± 1b,c 85 ± 3b,c 2.3 ± 0.2c 0.49 ± 0.03 0.21 ± 0.01b,c 4.5 ± 0.1 42 ± 1b,c,d 11 ± 0c 18 ± 2b,c 31 ± 1b,c 54 ± 8 264 ± 40 0.93 ± 0.17b,c 0.74 ± 0.10c 0.068 ± 0.012