Table 1.

Systemic and whole kidney data in micropuncture experimentsa

Parameter KCNE1 +/+ (n = 7) KCNE1 -/- (n = 7)
aMAP, mean arterial blood pressure; gluc, glucose; UV, UNaV, UCIV, UKV, or UglucV, urinary excretion of fluid, Na+, Cl-, K+, or glucose. * P < 0.05 versus KCNE1 +/+.
Body weight (g) 34 ± 1 32 ± 1
MAP (mmHg) 120 ± 2 124 ± 3
Heart rate (1/min) 558 ± 13 537 ± 16
Hematocrit (%) 47 ± 1 50 ± 1*
Plasma [Na+] (mM) 140 ± 1 140 ± 2
Plasma [Cl-] (mM) 124 ± 3 123 ± 2
Plasma [K+] (mM) 4.2 ± 0.1 4.2 ± 0.1
Plasma [gluc] (mM) 122 ± 4 105 ± 6*
GFR (μl/min per g body wt) 10.7 ± 1.2 9.6 ± 0.9
UV (nl/min per g body wt) 92 ± 13 126 ± 13
UNaV (nmol/min per g body wt) 10 ± 2 23 ± 5*
UCIV (nmol/min per g body wt) 16 ± 3 30 ± 4*
UKV (nmol/min per g body wt) 13 ± 2 14 ± 2
UglucV (ng/min per g body wt) 95 ± 7 142 ± 14*