Table 4.

Multivariate analysis of silica exposure for ANCA-SVV subgroupsa

Exposed Patients, Control Subjects (%)Matched-Pair Odds Ratio95% Confidence IntervalP Value
aMultivariate analysis for each subgroup was performed while controlling for smoking, pesticides, gasoline or other fuels, cleaning agents, glues, and paint products.
All ANCA (n = 65)46, 204.431.36 to 14.380.013
ANCA pattern
cytoplasmic ANCA (n = 34)59, 234.01.34 to 11.960.013
perinuclear ANCA (n = 31)35, 167.00.86 to 56.900.069
Disease category
Wegener's granulomatosis (n = 21)48, 243.50.73 to 16.800.118
microscopic polyangiitis (n = 44)48, 185.01.45 to 17.300.011
Airway involvement
lung and/or sinus (n = 39)44, 244.50.99 to 20.830.054
no lung or sinus (n = 26)50, 184.71.34 to 16.240.016