Table 2.

Yield and differentiation of peritoneal cells from the effluents of rats after 9 to 10 wk of PD fluid instillationa

Experiment AExperiment B
ControlBicarbonate/LactateStandardControlBicarbonate/LactateStandard
a Data are expressed as the median (range) of the total number of cells (× 106) in the effluent or the median (range) of the percentage of the total cell count. The ED2/ED1 ratio is expressed as mean ± SD. ND, not determined.
b Control versus standard, P < 0.05 (in the respective experiment).
c Control versus bicarbonate/lactate, P < 0.05.
Total cell count (× 106)18.0 (15.3 to 35.4)139.7 (14.3 to 162.9)84.0 (15.7 to 113.8)22.5 (19.7 to 27.8)19.6 (18.0 to 33.4)16.1 (10.0 to 29.0)
Macrophages (%)72.0 (64.0 to 80.0)71.0 (67.0 to 82.0)73.0 (63.0 to 82.0)70.0 (62.0 to 75.5)b,c75.0 (70.0 to 80.5)78.0 (75.5 to 82.5)
Lymphocytes (%)2.0 (0.0 to 6.0)4.5 (3.0 to 7.0)6.0 (2.0 to 9.0)2.0 (0.0 to 3.0)b,c7.0 (3.5 to 9.0)5.5 (3.5 to 10.0)
Neutrophils (%)0.0 (0.0 to 0.0)b,c17.0 (2.0 to 27.0)10.0 (5.0 to 13.0)0.0 (0.0 to 0.0)b,c1.0 (0.0 to 1.5)1.0 (0.0 to 5.0)
Eosinophils (%)17.0 (14.0 to 21.0)b2.0 (0.0 to 25.0)2.0 (0.0 to 16.0)16.0 (13.0 to 21.0)17.0 (12.0 to 19.5)14.0 (6.5 to 24.0)
Mastcells (%)7.5 (0.0 to 12.0)b,c0.0 (0.0 to 1.0)0.0 (0.0 to 1.0)11.0 (5.5 to 16.0)b,c0.5 (0.0 to 1.0)0.5 (0.0 to 2.5)
ED8+ cells (%)83.0 (76.0 to 86.0)76.5 (62.0 to 82.0)83.0 (68.0 to 85.0)75.0 (72.0 to 80.0)65.0 (55.5 to 74.0)72.8 (64.0 to 76.0)
Fc+ cells (%)70.0 (57.5 to 87.5)85.8 (76.0 to 89.5)79.0 (78.0 to 87.0)NDNDND
ED2/ED1 ratio0.39 ± 0.100.31 ± 0.250.20 ± 0.230.38 ± 0.090.43 ± 0.060.38 ± 0.10