Effects of oral administration of GBM to WKY rats with EAG on deposition of IgG on the GBM and deposition of fibrin in the glomeruli. Results are expressed as intensity of fluorescence at week 4 in individual animals
| Intensity of Immunostaining | ||||
|---|---|---|---|---|
| 3+ | 2+ | 1+ | — | |
| IgG | ||||
| positive control (n = 6) | 3 | 3 | 0 | 0 |
| negative control (n = 5) | 0 | 0 | 0 | 5 |
| GBM 0.5 mg (n = 6) | 4 | 2 | 0 | 0 |
| GBM 2.5 mg (n = 5) | 0 | 3 | 2 | 0 |
| GBM 5 mg (n = 6) | 0 | 1 | 2 | 3 |
| Fibrin | ||||
| positive control (n = 6) | 4 | 2 | 0 | 0 |
| negative control (n = 5) | 0 | 0 | 0 | 5 |
| GBM 0.5 mg (n = 6) | 3 | 3 | 0 | 0 |
| GBM 2.5 mg (n = 5) | 1 | 2 | 2 | 0 |
| GBM 5 mg (n = 6) | 0 | 0 | 1 | 5 |