Table 1.

Characteristics of the patients at randomization according to serum creatinine concentrationsa

Characteristic S-Creatinine
≤1.5 mg/dl (n = 18127) >1.5 mg/dl (n = 470) P Value
aValues are mean (SD) or percentage. MI, myocardial infarction; CHD, coronary heart disease.
Men/women 52/48 74/26 <0.0001
Mean age (yr) 61.4 (7.5) 64.4 (7.9) <0.0001
Systolic BP (mmHg) 169.6 (14.1) 171.4 (16.0) 0.008
Diastolic BP (mmHg) 105.4 (3.4) 105.4 (3.4) NS
Serum creatinine
μmol/L 87 (17) 173 (64) <0.0001
mg/L 0.98 (0.19) 1.96 (0.73) <0.0001
Serum cholesterol (mmol/L) 6.1 (1.1) 6.0 (1.1) NS
Previous MI (%) 1.4 4.3 <0.0001
Previous stroke (%) 1.1 4.3 <0.0001
Previous other CHD (%) 5.9 6.8 NS
Diabetes mellitus (%) 7.9 10.6 0.048
Smokers (%) 15.9 16.8 NS