Table 2.

Characteristics of patients at randomization according to their estimated baseline creatinine clearance

Creatinine Clearance
Characteristic >60 ml/min (n = 15770) ≤60 ml/min (n = 2821) P Value
Values are mean (SD) or percentage.
Men/women (%) 57/43 30/70 <0.0001
Mean age (yr) 60.3 (6.8) 68.4 (7.2) <0.0001
Systolic BP (mmHg) 169 (14.0) 173.4 (14.7) <0.0001
Diastolic BP (mmHg) 105.5 (3.4) 105.1 (3.3) <0.0001
Serum creatinine
μmol/L 85 (17) 109 (40) <0.0001
mg/L 0.96 (0.19) 1.24 (0.46) <0.0001
Serum cholesterol (mmol/L) 6.0 (1.1) 6.2 (1.2) <0.0001
Previous MI (%) 1.3 2.5 <0.0001
Previous stroke (%) 1.0 2.3 <0.0001
Previous other CHD (%) 5.5 8.3 <0.0001
Diabetes mellitus (%) 8.2 7.0 <0.0001
Smokers (%) 16.4 13.0 <0.0001