Table 3.

Events according to serum creatinine at baseline

Events No. of Events Event/1000 Patient Years Adjusted Relative Riska 95% CIaP Valuea
aP values, risk ratios, and confidence intervals (CI) are adjusted for achieved diastolic and systolic BP, age, gender, smoking habits, previous cardiovascular disease, diabetes, and total serum cholesterol.
bNonfatal myocardial infarction, nonfatal stroke, and all cardiovascular deaths.
Major cardiovascular eventsb
creatinine ≤1.5 mg/dl 626 9.2
creatinine >1.5 mg/dl 45 27.0 2.05 1.47-2.88 <0.001
All myocardial infarction
creatinine ≤1.5 mg/dl 197 2.9
creatinine >1.5 mg/dl 8 4.7 1.44 0.70-2.93 0.32
All stroke
creatinine ≤1.5 mg/dl 273 4.0
creatinine >1.5 mg/dl 16 9.5 1.58 0.88-2.84 0.13
Cardiovascular mortality
creatinine ≤1.5 mg/dl 241 3.5
creatinine >1.5 mg/dl 28 16.4 3.24 2.13-4.94 <0.001
Total mortality
creatinine ≤1.5 mg/dl 532 7.8
creatinine >1.5 mg/dl 50 29.3 2.86 2.10-3.89 <0.001