Table 1.

Plasma creatinine and lipids in 17 renal transplant patients during CsA treatment and TAC treatmenta

CsA 1 Tacrolimus CsA 2
aCsA, cyclosporin A; HDL, high-density lipoprotein; LDL, low-density lipoprotein; TAC, tacrolimus. Statistical analysis was performed by one-way ANOVA for repeated measurements.
bP < 0.01: TAC versus CsA 1.
cP < 0.001: TAC versus CsA 1.
dP < 0.001, CsA 2 versus TAC.
Plasma creatinine (μmol/L) 134 ± 49 148 ± 56b 141 ± 53
Total cholesterol (mmol/L) 6.1 ± 0.7 5.1 ± 0.8c 6.0 ± 0.9d
HDL (mmol/L) 1.41 ± 0.48 1.34 ± 0.47 1.41 ± 0.50
LDL (mmol/L) 3.84 ± 0.79 2.98 ± 0.75c 3.77 ± 0.80d
Triglycerides (mmol/L) 1.84 ± 1.23 1.58 ± 0.91 1.86 ± 1.56
CsA or TAC dose (mg/d) 290 ± 69 9 ± 2.6 290 ± 69
CsA or TAC trough level (ng/ml) 122 ± 45 9.9 ± 3.5 132 ± 38