Table 1.

Renal and biliary morphometrics

GenotypeKW/BW (%)CT/PT Cyst Ratio (DBA (+) Cysts/LTA (+) Cysts)PT CI/CT CIBDE
KW/BW, kidney weight as a percentage of body weight; CT, collecting tubule; PT, proximal tubule; DBA, Dolichos biflorus agglutinin; LTA, Lotus tetragonolubus; BDE, biliary ductal ectasia.
bpk -/-; cftr -/- (n = 5)15.3 ± 3.01.4 ± 0.12.0 ± 0.7/3.4 ± 0.92.6 ± 0.3
BW(g) = 4.8 ± 0.9
bpk -/-; cftr +/- (n = 9)14.3 ± 2.81.4 ± 0.22.1 ± 0.6/3.8 ± 1.02.5 ± 0.2
BW(g) = 7.6 ± 2.1
bpk +/+; cftr +/- (n = 30)1.5 ± 0.1---
BW(g) = 7.5 ± 2.1
bpk +/±; cftr -/- (n = 26)1.5 ± 0.1---
BW(g) = 7.3 ± 1.5