Table 3.

Effect of ammonia and/or SCH28080 on B-cell intracellular pHa

AmmoniaSCH28080nInitial pHiFinal pHiChange
aCortical collecting ducts were incubated in the presence of absence of ammonia for 30 min, then initial pHi was measured. SCH28080, if present, then was added to the luminal fluid, and after a 30-min incubation final pHi was measured.
bP < 0.05 versus 0.
PresentPresent57.12 ± 0.126.97 ± 0.02-0.15 ± 0.05b
AbsentPresent127.17 ± 0.097.15 ± 0.08-0.02 ± 0.04
PresentAbsent46.98 ± 0.056.97 ± 0.05-0.02 ± 0.02