Table 1.

Demographic and clinical characteristics of new ESRD patients (n = 3925), with and without CADa

CharacteristicStudy Population (% or mean ± SD)Missing Data (%)CAD Present (% or mean ± SD)CAD Absent (% or mean ± SD)
aCAD, coronary artery disease; ESRD, end-stage renal disease; PTH, parathyroid hormone; *, P < 0.001; **, P < 0.01. ***, P < 0.05.
bPresent or past smokers.
cRecorded before the first dialysis session.
dBefore first dialysis session, per the Modification of Diet in Renal Disease study formula (15).
eIncludes patients with history of left ventricular hypertrophy by electrocardiogram or echocardiogram.
fDefined as an enlarged heart by chest radiograph.
gIncludes history of peripheral vascular disease amputation, intermittent claudication, or absent pulses.
CAD383.5
Conventional factors
mean age (yr)*58 ± 16065 ± 253 ± 5
male gender (versus female)**5305651
diabetes mellitus (cause of ESRD)**4305237
hypertension (cause of ESRD)***2602427
predialysis systolic BP (mmHg)147 ± 212.2146 ± 22147 ± 21
predialysis diastolic BP (mmHg)*80 ± 122.376 ± 1281 ± 12
smokerb,**407.24637
total cholesterol (mg/dl)**194 ± 5510191 ± 54196 ± 56
LDL cholesterol (mg/dl)151 ± 9483147 ± 91153 ± 96
HDL cholesterol (mg/dl)59 ± 698353 ± 5863 ± 75
triglyceride (mg/dl)199 ± 14422.8200 ± 14198 ± 15
Uremic factors
hematocrit*30.? ± 6.63.831 ± 630 ± 6
serum albumin (g/dl)*3.46 ± 0.57103.38 ± 0.553.51 ± 0.58
serum phosphate (mg/dl)*5.5 ± 1.95.45.3 ± 1.85.7 ± 1.9
serum calcium (mg/dl)8.7 ± 1.05.28.7 ± 0.98.7 ± 1.1
serum PTH (ng/ml)*316 ± 37121.5278 ± 330339 ± 393
serum bicarbonate (mg/dl)*22 ± 4.710.822.4 ± 4.721.8 ± 4.8
serum creatinine (mg/dl)c,*8.4 ± 3.77.37.2 ± 2.79.2 ± 4.0
creatinine clearance (ml/min)d,*7 ± 2.916.18 ± 2.96.8 ± 2.8
Structural cardiac abnormalities
left ventricular hypertrophye,**20202914
cardiomegalyf,**2615.53918
Vascular/other comorbidities
peripheral vascular diseaseg,**214.63811
cerebrovascular disease**123198
pericarditis**2.8342
Pre-ESRD care
late referral (referral <4 mo before ESRD)23352224
visits to nephrologist (>2 versus less)42354142
visits to dietitian (>2 versus less)35353436
erythropoietin use before ESRD (yes versus no)16371617