Table 1. The effect of PKC, PI 3-kinase, and phosphatase inhibition on LX- stimulated phagocytosisa

% Increase in Phagocytosis ± SEM
a Mφ were treated with GF 109203X (20 μM), LY 294002 (10 μM), and Okadaic acid (100 nM) for 15 min at 37°C before stimulation with LXB4 (1 nM for 15 mins at 37°C). Data are % increase in phagocytosis versus control ± SEM (n = 5).
b P < 0.05 versus control.
LXB484.8 ± 2.0
GF4.0 ± 0.9b
GF 109203X + LXB44.0 ± 1.8b
LXB4141.4 ± 7.1
LY 29400231.0 ± 3.8b
LY 294002 + LXB468.9 ± 4.0b
LXB487.5 ± 11.6
Okadaic acid16.5 ± 10.4b
Okadaic acid + LXB45.8 ± 7.2b