FSGS (n = 7) | MCD (n = 6) | MNP (n = 8) | LN (n = 6) | DN (n = 6) | |
---|---|---|---|---|---|

^{a} Immunohistological staining for Smad6 and Smad7 was performed on a random series of human glomerular diseases. The staining was semiquantitatively ranked for equal or enhanced expression compared to normal specimen. Numbers represent cases in each group. FSGS, focal segmental glomerulosclerosis; MCD, minimal-change disease; MNP, membranous nephropathy; LN, lupus nephritis; DN, diabetic nephropathy. | |||||

Smad6 expression equal to normal | 4 | 2 | 1 | 2 | 3 |

Smad6 expression enhanced | 3 | 4 | 7 | 4 | 3 |

Smad7 expression equal to normal | 3 | 2 | 4 | 5 | 3 |

Smad7 expression enhanced | 4 | 4 | 4 | 1 | 3 |