Table 2.

Study 2: paired data of 10 patients studied before and 24 h after hemodialysis, in the absence or presence of ACE inhibitiona

ParameterBefore HDAfter HDBefore HD + ACEiAfter HD+ ACEiControl Subjects
a Data are compared to matched healthy subjects. HD, hemodialysis; ACEi, angiotensin-converting enzyme inhibition; SBP, systolic BP; MAP, mean arterial pressure; DBP, diastolic BP; PP, pulse pressure; C, central; PWV, pulse wave velocity.
b P < 0.05 compared with control subjects.
c P < 0.05 postdialysis compared with predialysis.
d P < 0.05 compared with predialysis without ACEi (effect of ACEi before volume reduction).
e P < 0.05 compared with postdialysis without ACEi (effect of ACEi after volume reduction).
f P < 0.05 compared with predialysis without ACEi (combined effect of volume reduction and ACEi).
Weight (kg)74.4 ± 13.072.4 ± 12.4c73.9 ± 13.072.4 ± 13.0c,f76.8 ± 10.2
Height (cm)173 ± 11177 ± 7
SBP (mmHg)152 ± 18b133 ± 12b,c139 ± 16b120 ± 12c,e,f122 ± 10
MAP (mmHg)108 ± 18b95 ± 10c95 ± 1187 ± 10c,f92 ± 7
DBP (mmHg)84 ± 1975 ± 11c73 ± 1067 ± 6b,c,f75 ± 5
PP (mmHg)67 ± 19b58 ± 15b,c66 ± 18b53 ± 11c,f47 ± 8
CSBP (mmHg)136 ± 18b117 ± 12c122 ± 17106 ± 12c,f112 ± 10
CDBP (mmHg)85 ± 1975 ± 10c73 ± 1068 ± 6b,c,f75 ± 6
CPP (mmHg)54 ± 20b46 ± 1652 ± 20b39 ± 10c,f37 ± 8
Heart rate (bpm)76 ± 11b77 ± 9b73 ± 11b77 ± 8b60 ± 6
Ejection duration (ms)318 ± 21301 ± 24c322 ± 29291 ± 29c323 ± 81
Aortic PWV (m/s)11.0 ± 3.5b9.8 ± 3.0b9.1 ± 2.1b,d8.0 ± 1.4c,e,f7.5 ± 1.1
Brachial PWV (m/s)9.4 ± 1.49.0 ± 1.38.3 ± 1.0d8.2 ± 1.8e,f8.4 ± 1.2
Augmentation index33 ± 627 ± 7c26 ± 1412 ± 23c,f25 ± 10
Viability index1.27 ± 0.24b1.40 ± 0.21b,c1.31 ± 0.18b1.46 ± 0.18b,c,f1.69 ± 0.18