Table 3.

Renal function postbiopsy—C4d-positive versus C4d-negative biopsiesa

Biopsy GroupsNumber of BiopsiesS-Creatinine μmol/L Mean ± SD (Median) 1 yr Postbiopsy
a The number of biopsies and s-creatinine levels refer to functioning grafts only. Differences between s-creatinine levels C4d positive versus negative: not significant.
All biopsies
 C4d-positive114197 ± 106 (169)
 C4d-negative266198 ± 105 (162)
Biopsies within 38 d posttransplantation
 C4d-positive55162 ± 56 (153)
 C4d-negative49177 ± 81 (149)
Initial biopsies
 C4d-positive65173 ± 78 (158)
 C4d-negative158182 ± 85 (153)
Biopsies from living donors
 C4d-positive42181 ± 75 (167)
 C4d-negative86191 ± 96 (160)
Biopsies from cadaveric donors
 C4d-positive72205 ± 120 (172)
 C4d-negative180201 ± 109 (163)
Biopsies from first transplants
 C4d-positive98196 ± 109 (169)
 C4d-negative239190 ± 97 (159)
Biopsies from 2nd and 3rd transplants
 C4d-positive16199 ± 92 (169)
 C4d-negative27253 ± 140 (224)
Transplant endarteritis
 C4d-positive32217 ± 131 (184)
 C4d-negative36194 ± 111 (163)
Transplant glomerulitis
 C4d-positive28231 ± 149 (165)
 C4d-negative20215 ± 105 (192)
Interstitial rejection
 C4d-positive55174 ± 58 (162)
 C4d-negative73218 ± 134 (173)