Table 1.

Biochemical and demographic profiles of SHD subjects and NHD subjectsa

SHD CohortNHD CohortP Value (Confidence Interval)b
a SHD, standard hemodialysis; NHD, nocturnal hemodialysis; PLP, pyridoxal 5′-phosphate; tHcy, total homocysteine.
b Based on two-sample t test.
c Mean (full range).
d Mean (95% confidence interval).
e Geometric mean (95% confidence interval).
f Confidence interval for ratio.
n3123
Age (yr)c45 (25 to 64)43 (20 to 65)0.59
Gender (% women)42300.39
PLP (nM)d133 (95 to 171)193 (142 to 145)0.052
Vitamin B12 (pg/ml)d732 (586 to 880)858 (715 to 1001)0.23
Folate (ng/ml)d42 (27 to 56)51 (32 to 69)0.45
Creatinine (mg/dl)d9.5 (8.1 to 10.9)5.1 (4.6 to 5.7)<0.001 (2.7 to 6.0)
Albumin (g/dl)d3.9 (3.8 to 4.1)4.5 (4.3 to 4.6)<0.001 (0.34 to 0.74)
tHcy (μM)e20.0 (17.5 to 22.8)12.7 (10.7 to 15.1)<0.001 (1.27 to 1.94)f