Table 1.

Fractional excretion of glucose and urinary excretion of proteins in control and AA-treated ratsa

Day 10Day 35
FEglucose (%)Urinary Protein Levels (g/mmol creatinine)FEglucose (%)Urinary Protein Levels (g/mmol creatinine)
a Data are the mean ± SEM for six rats/group. AA, aristolochic acids; FEglucose, fractional excretion of glucose.
b P < 0.01, compared with control rats.
c P < 0.05, compared with control rats.
Control0.16 ± 0.070.07 ± 0.010.05 ± 0.020.07 ± 0.01
Low-dose AA (1 mg/kg body wt)0.19 ± 0.030.08 ± 0.010.08 ± 0.020.10 ± 0.01
High-dose AA (10 mg/kg body wt)0.91 ± 0.370.17 ± 0.02b0.73 ± 0.20c0.25 ± 0.05b