Table 2.

Predicted change in mean hemoglobin level by renal functiona

CrClWomenMen
Change in Hemoglobin (g/dl)P ValueChange in Hemoglobin (g/dl)P Value
a Adjusted for age and race/ethnicity; values in parentheses are 95% confidence intervals for parameter estimates. CrCl, creatinine clearance.
CrCl > 80 ml/minReferenceReference
80 ≥ CrCl > 70 ml/min−0.0 (−0.1, 0.1)0.68−0.1 (−0.2, 0.0)0.16
70 ≥ CrCl > 60 ml/min−0.1 (−0.2, 0.0)0.08−0.2 (−0.3, −0.0)0.02
60 ≥ CrCl > 50 ml/min−0.1 (−0.2, 0.1)0.36−0.3 (−0.5, −0.1)0.007
50 ≥ CrCl > 40 ml/min−0.2 (−0.3, −0.0)0.01−0.4 (−0.6, −0.2)0.0005
40 ≥ CrCl > 30 ml/min−0.4 (−0.6, −0.2)<0.0001−0.8 (−1.1, −0.6)<0.0001
30 ≥ CrCl > 20 ml/min−1.0 (−1.2, −0.7)<0.0001−1.4 (−2.1, −0.6)0.0005
CrCl ≤ 20 ml/min−2.3 (−2.8, −1.9)<0.0001−2.7 (−3.8, −1.6)<0.0001