Table 1.

Ceiling doses (mg) of loop diuretics

Condition	Furosemide		Bumetanide		Torsemide
Condition	iv	po	iv	po	iv	po
After: Swan SK, Brater DC: Clinical pharmacology of loop diuretics and their use in chronic renal insufficiency. J Nephrol 6: 118–123, 1993, and Ellison D, Wilcox CS: Diuretic resistance. In: Therapy in Nephrology and Hypertension, edited by H.R. Brady and C.S. Wilcox. Philadelphia: W.B. Saunders, 1998, p. 665–674.
Chronic renal insufficiency
moderate (GFR 20 to 50 ml · min⁻¹)	120	240	3	3	50	50
severe (GFR > 20 ml · min⁻¹)	200	400	10	10	100	100
Nephrotic syndrome with normal GFR		120		3		50