Table 2.

Mortality rates for and relative hazards of death resulting from cardiovascular disease and all causes, according to urinary protein category

OverallUrinary Protein LevelP Trend
None/Trace30 to 299 mg/dl≥300 mg/dl
a Reference category.
b Adjusted for age, race, gender, systolic BP, total cholesterol level, body mass index, diabetes mellitus, history of myocardial infarction or stroke, current cigarette smoking, physical inactivity, and education level.
Person-years at risk115,688112,9252248516
All causes
    no. of patients 1876  17598037
    no. of deaths/1000 person-yr 10.9    10.426.650.5
    age-, race-, and gender-adjusted relative hazard    1.0a2.20 (1.75 to 2.77)3.46 (1.95 to 6.15)<0.001
    multivariate adjusted relative hazardb    1.0a1.64 (1.23 to 2.18)2.00 (1.13 to 3.55)<0.001
Cardiovascular disease
    no. of patients 1215  11335428
    no. of deaths/1000 person-yr 6.6    6.217.937.2
    age-, race-, and gender-adjusted relative hazard    1.0a2.38 (1.59 to 3.56)3.89 (2.30 to 6.58)<0.001
    multivariate adjusted relative hazardb    1.0a1.57 (0.99 to 2.48)1.77 (0.97 to 3.21)0.02
Coronary disease
    no. of patients 594    5542713
    no. of deaths/1000 person-yr 3.1    3.08.814.5
    age-, race-, and gender-adjusted relative hazard    1.0a2.48 (1.47 to 4.18)3.17 (1.53 to 6.60)<0.001
    multivariate adjusted relative hazardb    1.0a1.47 (0.79 to 2.75)1.23 (0.55 to 2.71)0.29
Congestive heart failure
    no. of patients 268    248164
    no. of deaths/1000 person-yr 1.3    1.24.95.2
    age-, race-, and gender-adjusted relative hazard    1.0a3.72 (2.07 to 6.69)3.08 (0.96 to 9.95)0.001
    multivariate adjusted relative hazardb    1.0a2.28 (1.32 to 3.94)1.33 (0.43 to 4.06)0.03