Table 1.

Cyclosporine dose and whole blood predose levels in 54 pediatric renal transplant recipients at the four pharmacokinetic sampling periods posttransplanta

Cyclosporine APharmacokinetic Sampling Period
1 wk3 wk3 mo6 mo
a Data are median (range).
Dose (mg/kg per d)7.85 (3.13 to 17.7)6.98 (3.81 to 20.7)5.90 (2.65 to 13.4)5.70 (3.06 to 13.8)
Predose level (ng/ml)185 (31 to 452)193 (126 to 306)172 (73 to 258)144 (85 to 199)